ID F6DJA4_THETG Unreviewed; 722 AA.
AC F6DJA4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN OrderedLocusNames=Ththe16_2124 {ECO:0000313|EMBL:AEG34501.1};
OS Thermus thermophilus (strain SG0.5JP17-16).
OG Plasmid pTHTHE1601 {ECO:0000313|EMBL:AEG34501.1,
OG ECO:0000313|Proteomes:UP000009233}.
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=762633 {ECO:0000313|EMBL:AEG34501.1, ECO:0000313|Proteomes:UP000009233};
RN [1] {ECO:0000313|Proteomes:UP000009233}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SG0.5JP17-16 {ECO:0000313|Proteomes:UP000009233};
RC PLASMID=Plasmid pTHTHE1601 {ECO:0000313|Proteomes:UP000009233};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Teshima H., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Allgaier M., Hugenholtz P., Singer S.,
RA Gladden J., Woyke T.;
RT "Complete sequence of plasmid of Thermus thermophilus SG0.5JP17-16.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR EMBL; CP002778; AEG34501.1; -; Genomic_DNA.
DR AlphaFoldDB; F6DJA4; -.
DR KEGG; tts:Ththe16_2124; -.
DR PATRIC; fig|762633.3.peg.2115; -.
DR HOGENOM; CLU_023291_1_0_0; -.
DR Proteomes; UP000009233; Plasmid pTHTHE1601.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11070:SF30; F-BOX DNA HELICASE 1; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plasmid {ECO:0000313|EMBL:AEG34501.1}.
FT DOMAIN 523..635
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13361"
FT REGION 131..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 81106 MW; B1A94DEE05D39510 CRC64;
MLSPFGGEEE TKAIPLEEEI LLAWRVFSAA LPPNFLAPVS ASLHTLVREA EGKEGAELEA
YAWERLEELA RTSVVKDAIQ SFLEVAAEKP EVLRAGLLWF RTWNRLSPEE REALYRKAER
FKPTAELASK ASFLQGPPPP PKPLSPSVQA ARSSPPRFTP TPEQEEAVRA FLSREDMKLV
AVAGSGKTTT LRLMAQSAPK ERLLYVAFNR SVRDEAERTF PGNVEVLTLH GLAHRHVVRG
SGAYQRKLAA RNGRVTPGDV LEALELPRER YALAYVIRST LEAFLRSASE VPTPAHIPPE
YREVLQRRDK DPFSERYVLK AVRLIWKLMQ DPDDSFPLSF DGFVKIWAQA GAKIRGYDAV
LVDEAQDLSP VFLQVLEAHR GELRRVYVGD PRQQIYGWRG AVNAMDKLDA PERKLTWSFR
FGEDLARGVR RFLAHVGSPI ELHGKAPWDT EVSLARPEPP YTALCRTNAG AVEAVTSFLL
EEGREGARVF VVGGVDEIAW LLRDAHLLKV GGEREKPHPE LALVENWEEL EELAKEVNHP
QARMLVRLAR RYDLLELARL LKHAQADEEG KADLVVSTLH KAKGREWDRV VLWGDFIPVW
DEKVREFYRK QGALDELKEE ENVVYVALTR ARRFLGLDQL PDLHERFFQG EGLVKPPSVS
PLSVGGAGVS ADLLRELEVR VLAKLEDRLK EVAEVLAALL VEEASKAVAE AMREMGLLGE
EG
//
