ID F6EN53_HOYSD Unreviewed; 285 AA.
AC F6EN53;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-chole st-24-enoyl-CoAhydratase {ECO:0000313|EMBL:AEF39370.1};
GN OrderedLocusNames=AS9A_0918 {ECO:0000313|EMBL:AEF39370.1};
OS Hoyosella subflava (strain DSM 45089 / JCM 17490 / NBRC 109087 / DQS3-9A1)
OS (Amycolicicoccus subflavus).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Hoyosellaceae;
OC Hoyosella.
OX NCBI_TaxID=443218 {ECO:0000313|EMBL:AEF39370.1, ECO:0000313|Proteomes:UP000009235};
RN [1] {ECO:0000313|EMBL:AEF39370.1, ECO:0000313|Proteomes:UP000009235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45089 / DQS3-9A1 {ECO:0000313|Proteomes:UP000009235};
RX PubMed=21725023; DOI=10.1128/JB.05388-11;
RA Cai M., Chen W.M., Nie Y., Chi C.Q., Wang Y.N., Tang Y.Q., Li G.Y.,
RA Wu X.L.;
RT "Complete genome sequence of Amycolicicoccus subflavus DQS3-9A1T, an
RT actinomycete isolated from crude oil-polluted soil.";
RL J. Bacteriol. 193:4538-4539(2011).
CC -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC {ECO:0000256|ARBA:ARBA00005254}.
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DR EMBL; CP002786; AEF39370.1; -; Genomic_DNA.
DR RefSeq; WP_013805719.1; NC_015564.1.
DR AlphaFoldDB; F6EN53; -.
DR STRING; 443218.AS9A_0918; -.
DR KEGG; asd:AS9A_0918; -.
DR eggNOG; COG2030; Bacteria.
DR HOGENOM; CLU_040078_1_1_11; -.
DR OrthoDB; 5522043at2; -.
DR Proteomes; UP000009235; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd03448; HDE_HSD; 1.
DR Gene3D; 3.10.129.10; Hotdog Thioesterase; 1.
DR InterPro; IPR029069; HotDog_dom_sf.
DR InterPro; IPR039569; MaoC-like_dehydrat_N.
DR InterPro; IPR002539; MaoC-like_dom.
DR PANTHER; PTHR13078:SF56; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2; 1.
DR PANTHER; PTHR13078; PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED; 1.
DR Pfam; PF13452; MaoC_dehydrat_N; 1.
DR Pfam; PF01575; MaoC_dehydratas; 1.
DR SUPFAM; SSF54637; Thioesterase/thiol ester dehydrase-isomerase; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009235}.
FT DOMAIN 50..138
FT /note="N-terminal of MaoC-like dehydratase"
FT /evidence="ECO:0000259|Pfam:PF13452"
FT DOMAIN 164..272
FT /note="MaoC-like"
FT /evidence="ECO:0000259|Pfam:PF01575"
FT REGION 148..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 285 AA; 30490 MW; 3D7AF912B028359E CRC64;
MPIDPSVAVG AELGQTSFSW ESSDVLLYHL GIGAGADPLD SRELRYAYEK DLRVLPTFAT
VAATMRASEP PRVSFPGIEI DLAKVVHGSQ SVTAHRPLPV AGKATASSRI TDVFDKGKAA
VIVQETDVTS EDGEPLWTAQ SRIFARGEGG FGGDRGPSER IDLPDREPDV TVSTATLPQQ
ALLYRLCGDR NPLHADPDFA QAAGFDQPIL HGLCTYGVVA KAVTDAVLDG DPTLVRSWSA
RFAGIVLPGE TLRTKIWELD GKFIVSTESV ERSAPVLADA VLQRV
//
