ID F6FSB1_ISOV2 Unreviewed; 297 AA.
AC F6FSB1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Transketolase central region {ECO:0000313|EMBL:AEG43052.1};
GN OrderedLocusNames=Isova_0248 {ECO:0000313|EMBL:AEG43052.1};
OS Isoptericola variabilis (strain 225).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Isoptericola.
OX NCBI_TaxID=743718 {ECO:0000313|Proteomes:UP000009236};
RN [1] {ECO:0000313|EMBL:AEG43052.1, ECO:0000313|Proteomes:UP000009236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=225 {ECO:0000313|Proteomes:UP000009236};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Siebers A., Allgaier M., Thelen M.,
RA Hugenholtz P., Gladden J., Woyke T.;
RT "Complete sequence of Isoptericola variabilis 225.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002810; AEG43052.1; -; Genomic_DNA.
DR AlphaFoldDB; F6FSB1; -.
DR STRING; 743718.Isova_0248; -.
DR KEGG; iva:Isova_0248; -.
DR eggNOG; COG3958; Bacteria.
DR HOGENOM; CLU_009227_1_1_11; -.
DR Proteomes; UP000009236; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR PANTHER; PTHR43825:SF1; TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009236}.
FT DOMAIN 1..166
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 297 AA; 30931 MW; 87B8A33CFC088BDA CRC64;
MSMRDRFYAE LDPVLERHPD AVVVLAVIGA AQASRASARH PGRVVDVGIR EQAMVGVAGG
LALAGLRPIV HTYAPFLVER AYEQVKLDLG HQDVGALLVS TGASYDASTA GRTHQAPADV
ALVAALPGWG VHVPGHADEL AALVHREAGA TGRAYVRMSA QHNARAYPVD GRLHLVRDGG
AGSPLVVAVG PMLDTVLAAV ADLPVRVAYT ATPHPLDTEG LRALAGPVPA LAVVEPYLEG
TSAHAVAAAL ADRPSRAVHV GVPRDAELRR YGTPRDHAAA HGLDAAGVRR RVKELLG
//
