ID F6FW10_ISOV2 Unreviewed; 316 AA.
AC F6FW10;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=1-deoxy-D-xylulose-5-phosphate synthase {ECO:0000313|EMBL:AEG44480.1};
DE EC=2.2.1.7 {ECO:0000313|EMBL:AEG44480.1};
GN OrderedLocusNames=Isova_1731 {ECO:0000313|EMBL:AEG44480.1};
OS Isoptericola variabilis (strain 225).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales;
OC Promicromonosporaceae; Isoptericola.
OX NCBI_TaxID=743718 {ECO:0000313|Proteomes:UP000009236};
RN [1] {ECO:0000313|EMBL:AEG44480.1, ECO:0000313|Proteomes:UP000009236}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=225 {ECO:0000313|Proteomes:UP000009236};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Zeytun A., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Siebers A., Allgaier M., Thelen M.,
RA Hugenholtz P., Gladden J., Woyke T.;
RT "Complete sequence of Isoptericola variabilis 225.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002810; AEG44480.1; -; Genomic_DNA.
DR RefSeq; WP_013838872.1; NC_015588.1.
DR AlphaFoldDB; F6FW10; -.
DR STRING; 743718.Isova_1731; -.
DR KEGG; iva:Isova_1731; -.
DR eggNOG; COG3958; Bacteria.
DR HOGENOM; CLU_009227_1_1_11; -.
DR Proteomes; UP000009236; Chromosome.
DR GO; GO:0008661; F:1-deoxy-D-xylulose-5-phosphate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR PANTHER; PTHR43825:SF1; TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009236};
KW Transferase {ECO:0000313|EMBL:AEG44480.1}.
FT DOMAIN 10..175
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 316 AA; 32867 MW; 32F4C7E440DC9C6D CRC64;
MTTTAPAALH DCRDAYVGAL VELAAEDDRI VAVVNDSVGS SKLAPFAEKY PERLINVGIA
EQDMVGVAAG LANGGKIPFV SAASCFLTAR AMEQIKVDAA YSNHHMVLCG MSPGMAYGEL
GPTHHSIEDL AWLRTIPGLT VVVPADPAET AQAIRWAAGH DGPVFVRVSR MGVPDVNPGG
YEFTPGKAVT LREGSDVTIV ATGTVVSRAL EAADVLGENG VSARVISMPT IKPLDSTAIL
AAAAETRGIV TVEEALTSGL GGAVAEVVVQ QHPVPVRFVG VRDQFAPTGS VGWLLDHFGI
NSEGIVRAAK DLLDRV
//
