ID F6GB02_RALS8 Unreviewed; 795 AA.
AC F6GB02;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Cation (Cadmium)-transporting atpase (Cadmium efflux atpase) {ECO:0000313|EMBL:AEG72135.1};
GN Name=cadA {ECO:0000313|EMBL:AEG72135.1};
GN OrderedLocusNames=RSPO_m01500 {ECO:0000313|EMBL:AEG72135.1};
OS Ralstonia solanacearum (strain Po82).
OG Plasmid {ECO:0000313|Proteomes:UP000007953}.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=1031711 {ECO:0000313|EMBL:AEG72135.1, ECO:0000313|Proteomes:UP000007953};
RN [1] {ECO:0000313|EMBL:AEG72135.1, ECO:0000313|Proteomes:UP000007953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Po82 {ECO:0000313|Proteomes:UP000007953};
RX PubMed=21685279; DOI=10.1128/JB.05384-11;
RA Xu J., Zheng H.J., Liu L., Pan Z.C., Prior P., Tang B., Xu J.S., Zhang H.,
RA Tian Q., Zhang L.Q., Feng J.;
RT "Complete genome sequence of the plant pathogen Ralstonia solanacearum
RT strain Po82.";
RL J. Bacteriol. 193:4261-4262(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|ARBA:ARBA00006024,
CC ECO:0000256|RuleBase:RU362081}.
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DR EMBL; CP002820; AEG72135.1; -; Genomic_DNA.
DR AlphaFoldDB; F6GB02; -.
DR KEGG; rsn:RSPO_m01500; -.
DR PATRIC; fig|1031711.3.peg.4681; -.
DR HOGENOM; CLU_001771_6_4_4; -.
DR Proteomes; UP000007953; Plasmid megaplasmid.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015662; F:P-type ion transporter activity; IEA:UniProt.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR48085; CADMIUM/ZINC-TRANSPORTING ATPASE HMA2-RELATED; 1.
DR PANTHER; PTHR48085:SF5; CADMIUM_ZINC-TRANSPORTING ATPASE HMA2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Cell membrane {ECO:0000256|RuleBase:RU362081};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Plasmid {ECO:0000313|EMBL:AEG72135.1};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 165..183
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 189..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 215..236
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 390..408
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 420..449
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 743..763
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 769..788
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 795 AA; 82018 MW; 39E292BB73D3CF8D CRC64;
MTAYHHHPAS SMTSHDHADA KPAKSSCGGC CGHDHPAARD TAAHPAPAHA PHPGRDHAHE
PHAAAAPVDA AVLARASGRT RLRIAQMDCP TEERMIRARL GNAAGVVALD FNLLERHLTI
HHTVDDIAPF LEALRAIGMD GEVLEAHDRA AAVSEAAPGG VSRRTWLLGV GGVAAFGAEA
IAWSLGDHAW PVLALALASI GLAGGPTLRK GWIALRAFTF NINFLMAVAV IGALLIGKWA
EAAMVIFLFA VAEAIEARAL VRARDAVRAL TAIAPDTAEV SDGAGGWRAV AVDAVALGMR
LRVRTGSRVP VDARIVAGRA ALDESPVTGE SLPVEKAIGD AILAGTIVTD GVIEAEATAV
AADSTLARIA AAIQEAQAQR APTQRFVDQF ASIYTPAMML LALAVAVIGP QVTADGWLAW
AYRALVLLVI ACPCALVIST PVTVVSGLAA AARRGIVVKG GVYLESGRRL RALALDKTGT
LTAGRPVLDT VALPDGTSRP VVSLDAATDV VQLRALGVAA ALDAHTTHPI ALAIVQAAAA
HGAAQDRPVE DLSVLPGRGV AGTLDGVRWH LGNAALVAER GWDTAAWRQA AEQLQAVGMS
AVTLCDAGGA VALFGVRDRE RAESAEAIAG LRALQVHPVM LTGDDRCAAQ AIAQAIGIDA
VHAEQLPADK QRVVGELAAQ YGFVGMVGDG INDAPALARA DIGFAMGAAG TATALEAADV
AIMDDDPRKL AAFIRISRRT VAVLRQNIAL ALGIKAVFLA LAVAGEATLW MAIFADVGAS
LLVVFNGLRV MRVRA
//
