ID F6H781_VITVI Unreviewed; 2329 AA.
AC F6H781;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Lysine-specific demethylase JMJ25 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_16s0098g01830 {ECO:0000313|EMBL:CCB48045.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB48045.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01002}.
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DR EMBL; FN595247; CCB48045.1; -; Genomic_DNA.
DR PaxDb; 29760-VIT_16s0098g01830-t01; -.
DR eggNOG; KOG1356; Eukaryota.
DR HOGENOM; CLU_229878_0_0_1; -.
DR InParanoid; F6H781; -.
DR Proteomes; UP000009183; Chromosome 16.
DR ExpressionAtlas; F6H781; baseline and differential.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0000118; C:histone deacetylase complex; IBA:GO_Central.
DR GO; GO:0031490; F:chromatin DNA binding; IBA:GO_Central.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IBA:GO_Central.
DR GO; GO:0003712; F:transcription coregulator activity; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 2.60.120.650; Cupin; 2.
DR InterPro; IPR017956; AT_hook_DNA-bd_motif.
DR InterPro; IPR045109; JHDM2-like.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR014977; WRC_dom.
DR InterPro; IPR018866; Znf-4CXXC_R1.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR12549:SF66; ENBP1 PROTEIN; 1.
DR PANTHER; PTHR12549; JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF10497; zf-4CXXC_R1; 1.
DR SMART; SM00384; AT_hook; 8.
DR SMART; SM00558; JmjC; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 2.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS51667; WRC; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 1..44
FT /note="WRC"
FT /evidence="ECO:0000259|PROSITE:PS51667"
FT DOMAIN 1075..1122
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 1522..2252
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT REGION 154..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 682..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 756..779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1014..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1610..1629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2104..2129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2288..2317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..279
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2295..2309
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2329 AA; 255619 MW; A68590294EDD3E05 CRC64;
MEDERCRRRG SPNWRCSERA LPGKTLCEKH LFCQLIRNRV KTARLAEGRD GEVGRPSGKQ
KLAAAGEEMV GGGGKEDRGF SGEILAAGEG GGGEVVGGGE MPEGFGGGMW GWFGGDEGGN
DGNALGSGGV MGGSAGDGNG REVDGGGVGE RGVASGNWAT GRGNGGGVVE SGGDGDWVSS
GGIGGCSREE AGGNGSGDVR LIESLAGHSG GNEGGGEEVV KGGEDSGRAA GGGGLVGYPK
EVTGGIGGNS GGSGGGIGGI ESRSDGNGHG DDVGEKKKRR GRPRGSKTRR KGEEVPGQSR
ESTGGNGGGN DGNGCNASGN IGGDEIVVLK KRKLGRPKGS KTRRNVIDGE IVELPIGNWG
GSEVIGGLSS GNGRGEIEGT GDLSGGSGRG SGEGIGGLPG GDGSGGEIMV KRRKLGRPKG
SNTRRRIPDG RELQVWAGET VENDGLALDL EGNRWKSGAF HGGNNGEGWK VKHGRGRPKG
WKKKGRKRKV FYGGELRALE GVKKRGRKRK IVDGEELWDL KGLEKRGRKG GIFYGKELQG
SSCEARMVDL LATLQSFAPY SGAVLAEYIK KQYAAITSVP SKQKVWRQPD LAKMVGLLAT
LRDVVPYRGE VLAENFLYFK WRSSISALEY LAPCRGGVLA EYFMYRERSS SIPYDDIYKC
EFDEAPLVTE EIQDQSVQGI RVNEGPSHSE GIGVGEGPSS TEGIQGQYGG AAGGNDGGKL
GAKEFLGGFG AFARQKDGGY GFSRLKNKCR RLKGSNNGEE IGGWSGEASR ENGPQKEIQG
WSSEACCRND GDEMVSLRGR CDRPNSSEDW MNELNRSGGA TCTIDRRSEI ISSEGKCGWP
QVIENKRTIL AAEQDGIIPF EVTGWNDMGD ETEGLENKKS GLIAIEDRGL PGEVIGRDEK
PNEIFRQKAK RGRPKGSKNR IPCIPKEEQS QATASNFLGG NNSGDVNISW KRKPGRPKGS
KNKKVILNGE ALNKIPMLNQ EHQMPVSKIE EDLNKEGSLQ VEYVRDCGNA QMSNGELLTD
TGNVHKRPRG RPKKLKDHRG ESNCIKEGKF NENGLANSGL SDASNGKREQ RSLMCHQCLR
HAKSGVVVCS SCKKKRYCYE CLAKWYPEKT REDIRNACPF CRCICNCRMC LKQDLVVMTG
HGEADTNIKL QKLLYLLDRT LPLLRHIHGE QSSEIHVEAQ IRGAQLTEED IMRSILDKDD
RVYCDNCNTS IVNLHRSCPN PDCSYDLCLT CCRELRKGLQ PGGNEAESSH QQFVERVNGQ
GTEVKGRIPA HDERYGWESD GAHPTNNYAA DTCDFPDWRV NMDGSIPCPP KARGGCGTET
LELRRIFEPN WVDHLIKSAE DLTMNFGSPD IDFSQGCSLC LPTASTGSGE KHCEVRRAAF
RENSHDDFLY CPNSACLGDN EIEHFQMHWM RGEPVIVRNV LEKTSGLSWD PMVMWRAFRG
ATKVLKEDAL SVKAIDCFDW CEVQINIFQF FKGYLQGRRH KSGWPEMLKL KDWPPSNSFD
ECLPRHGAEF IAMLPYSDYT NPKSGLLNLA TKLPDVLKPD LGPKTYIAYG SLEELGRGNS
VTKLHCDISD AVNVLTHTAK VNITPLQSKI MNKLQKKYEA EDLLELYGGA HDASDTTGKE
TTEQSQKDET MDCVYSAKEN TVGIDSLFLG SLNEKEEKHS EQEDRRTLPL LDSMGLGTMS
SDRDYILEDL ALESTVMVNC EKQSVGDLNT EFQICDLEKH ESNLSLLEKD CGITHVLVKK
QAELKRCSLQ FGGSVEDSLL HESINLEKTP PNGHKIGNFL GMSGKEDRYY SMNNQPDTCT
SYIDGSSSIV RNCMNGELNI QGIEQPGFKE FSSFICRDVD ERNFSLSGEI NVDADCLATK
DLCCPHQLGA ENGIAKTDSF NQEYSQPPNV ALKNNLNNED VLDVIFLGTE RDYEPELMKS
DLDEKGTRFN YAVNCRDVTE RNFSLPDRMD FNPHCLDTEE LCCADRLDVQ DEIVERDSAH
KQEYNQPPNL LGTRMLISGK DGLQGMFSGN CWESGPKPDT RVLDVGPDCF AKSRDVSEKD
LFLPEERDRD PNCPAAEEFW SGNGFDAKNA RTERGLCNQE YFHLSNEKAE MRFVSEKSPL
EATFSGNEAN HSESMKPGSS NVRDSVQSND HSEVAYGGAV WDIFRRQDVP KLIEFLRKHQ
KEFRHINNLP VDSVIHPIHD QTLYLTERHK KQLKEEYNVE PWTFEQYLGE AVFIPAGCPH
QVRNRQSCIK VALDFVSPDN VQECIRLTEE FRLLPKDHRA KEDKLEVKKM ALYAVNVAVD
EAKNLISKLE QGRPAPEPGP GPRPEPEPEP EPAAVTERIW QQQQKCIRV
//
