ID F6H9H7_VITVI Unreviewed; 737 AA.
AC F6H9H7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN OrderedLocusNames=VIT_04s0069g00790 {ECO:0000313|EMBL:CCB48870.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB48870.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the cyclic nucleotide-gated cation channel (TC
CC 1.A.1.5) family. {ECO:0000256|ARBA:ARBA00010486}.
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DR EMBL; FN595500; CCB48870.1; -; Genomic_DNA.
DR RefSeq; XP_010648838.1; XM_010650536.2.
DR RefSeq; XP_019075139.1; XM_019219594.1.
DR AlphaFoldDB; F6H9H7; -.
DR STRING; 29760.F6H9H7; -.
DR PaxDb; 29760-VIT_04s0069g00790-t01; -.
DR EnsemblPlants; Vitvi04g00736_t001; Vitvi04g00736_P001; Vitvi04g00736.
DR GeneID; 100267557; -.
DR Gramene; Vitvi04g00736_t001; Vitvi04g00736_P001; Vitvi04g00736.
DR KEGG; vvi:100267557; -.
DR eggNOG; KOG0498; Eukaryota.
DR HOGENOM; CLU_013069_3_0_1; -.
DR InParanoid; F6H9H7; -.
DR OrthoDB; 3076617at2759; -.
DR Proteomes; UP000009183; Chromosome 4.
DR ExpressionAtlas; F6H9H7; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45651:SF9; CYCLIC NUCLEOTIDE-GATED ION CHANNEL 14-RELATED; 1.
DR PANTHER; PTHR45651; CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED-RELATED; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 99..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 222..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 386..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 494..575
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 662..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..678
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 681..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..730
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 85312 MW; 033EC899BD0DA6C1 CRC64;
MHMMNQMEFK KEKLVRFCSD EKQNLEVSWE KGESQPVERP VSYKVLPSLL NPEGRAGEKN
RTYGTLSFGR FKVFPESHEP WRKRILDPGS DIFLQWNRVF LFSCLVALFV DPLFFYLPTV
VGDGNSSCVK TDLNLGIVVT CFRTIADVFY LLHMAIKFRT AYVSPSSRVF GRGELVMDPK
EIARRYLKSD FFIDLVATLP LPQIVIWFVI PAIRSSHADH TNNALVLIVL LQYVPRLYLI
FPLSSQIIKA TGVVTKTAWA GAAYNLLLYM LASHVLGASW YLLSIERHAT CWKSVCRKEL
GPIRCFLRFL DCGTLDDDDR RKWNNSTFVF SHCDPSKDIS FNYGIFGDAI KKNVVYSKFL
EKYFYCLWWG LQNLSSYGQS LSTSTFIGET AFAILIAILG LVLFAHLIGN MQTYLQSITV
RLEEWRLKRR DTEEWMRHRQ LPQDLRERVR RFVQYKWLAT RGVDEESILR ALPTDLRRDI
QRHLCLDLVR RVPFFSQMDD QLLDAICERL VSSLSTQGTY IVREGDPVTE MLFIIRGRLE
SSTTNGGRTG FFNSITLRPG DFCGEELLAW ALLPKITQNL PSSTRTVRAL VEVEAFALRA
EDLKFVANQF RRLHSKKLQH TFRFYSHHWR TWAACFIQAA WRRYKKRIMA KNLSMRESFS
FADDDDHADD EDETEQEDEG SSTKSNSSQA KQHLGVTILA SRFAKNTRRG AQKVKDVEMP
KLQKPEEPDF SIEPDDY
//
