ID F6HGS6_VITVI Unreviewed; 761 AA.
AC F6HGS6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 24-JAN-2024, entry version 82.
DE RecName: Full=Subtilisin-like protease SBT1.8 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_11s0016g00960 {ECO:0000313|EMBL:CCB51390.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB51390.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; FN595756; CCB51390.1; -; Genomic_DNA.
DR RefSeq; XP_002278292.1; XM_002278256.3.
DR AlphaFoldDB; F6HGS6; -.
DR STRING; 29760.F6HGS6; -.
DR MEROPS; S08.A24; -.
DR PaxDb; 29760-VIT_11s0016g00960-t01; -.
DR EnsemblPlants; Vitvi11g00071_t001; Vitvi11g00071_P001; Vitvi11g00071.
DR GeneID; 100264662; -.
DR Gramene; Vitvi11g00071_t001; Vitvi11g00071_P001; Vitvi11g00071.
DR KEGG; vvi:100264662; -.
DR eggNOG; ENOG502QRTY; Eukaryota.
DR HOGENOM; CLU_000625_4_6_1; -.
DR InParanoid; F6HGS6; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000009183; Chromosome 11.
DR ExpressionAtlas; F6HGS6; baseline and differential.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF335; SUBTILISIN-LIKE PROTEASE SBT1.8; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..761
FT /note="Subtilisin-like protease SBT1.8"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003335799"
FT DOMAIN 24..100
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 130..581
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 372..454
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 655..755
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT REGION 196..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 138
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 213
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 540
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 761 AA; 81102 MW; D04112A4579B9E9A CRC64;
MASVVWLFSF WFACFSLSVM AKRTYIVQMN HRQKPLSYAT HDDWYSASLQ SISSNSDDLL
YTYSTAYHGF AASLDPEQAE ALRKSDSVMG VYEDEVYSLH TTRSPEFLGL DTELGLWAGH
RTQDLNQASQ DVIIGVLDTG VWPDSRSFDD SGMTEVPARW RGKCEEGPDF QASSCNKKLI
GAQSFSKGYR MASGGNFVKK SKEKESPRDV DGHGTHTAST AAGAHVSNAS LLGYASGTAR
GMATHARVAA YKVCWSTGCF GSDILAGMDR AIVDGVDVLS LSLGGGSGPY YRDTIAIGAF
TAMEMGIFVS CSAGNSGPSK ASLANVAPWI MTVGAGTLDR DFPAYALLGN GKKITGVSLY
SGRGMGKKPV SLVYSKGNST SNLCLPGSLQ PAYVRGKVVI CDRGINARVE KGLVVRDAGG
VGMILANTAV SGEELVADSH LLPAVAVGRK VGDVLRAYVK SVANPTALLS FGGTVLNVRP
SPVVAAFSSR GPNLVTPQIL KPDLIGPGVN ILAAWSEALG PTGLEKDTRK TQFNIMSGTS
MSCPHISGVA ALIKAAHPEW SPSAVKSALM TTAYTRDNTK SPLRDAADGG LSTPLAHGSG
HVDPQKALSP GLVYDISTQD YVAFLCSLDY TIEHVRAIVK RQNITCSRKF SDPGELNYPS
FSVLFGSKGF VRYTRELTNV GAADSVYQVA VTGPPSVGVV VRPSTLVFKN VGEKKRYTVT
FVAKKGKKVQ NRMTRSAFGS IVWSNTQHQV KSPVAYAWTQ L
//
