ID F6HLE6_VITVI Unreviewed; 1116 AA.
AC F6HLE6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN OrderedLocusNames=VIT_08s0007g07240 {ECO:0000313|EMBL:CCB55207.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB55207.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; FN595991; CCB55207.1; -; Genomic_DNA.
DR RefSeq; XP_002281591.1; XM_002281555.3.
DR AlphaFoldDB; F6HLE6; -.
DR STRING; 29760.F6HLE6; -.
DR PaxDb; 29760-VIT_08s0007g07240-t01; -.
DR EnsemblPlants; Vitvi08g01798_t001; Vitvi08g01798_P001; Vitvi08g01798.
DR GeneID; 100264144; -.
DR Gramene; Vitvi08g01798_t001; Vitvi08g01798_P001; Vitvi08g01798.
DR KEGG; vvi:100264144; -.
DR eggNOG; KOG2171; Eukaryota.
DR HOGENOM; CLU_003794_0_1_1; -.
DR InParanoid; F6HLE6; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000009183; Chromosome 8.
DR ExpressionAtlas; F6HLE6; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527:SF102; BETA-3, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR Pfam; PF13513; HEAT_EZ; 3.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 42..114
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 419..457
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 924..957
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1116 AA; 123527 MW; BB594F3E845CB849 CRC64;
MASDPTPLQL NQIAAILGPD PVHFEALISH LMATANDQRS QAEALFNLCK QTHPDSLVLK
LAILLQSSPH PEARAMAAIL LRKQLTRDDS YLWPNLSATT QANLKSILLD CVQRETAKTI
SKKLCDTVSE LASGILPDGG WPELLPFMFQ CVTSSNFKLQ EAALLIFAQL SQYIGETLLP
HLDTLHSVFL QSLASSMNSD VRIAALGAAI NFIQCLSNAA ERDKFQDLLP LMMQTLTEAL
NSSQEATAQE ALELLIELAG TEPRFLRRQL VEVVGSMLQI AEAELLEEGT RHLAVEFVIT
LAEARERAPG MIRKLPQFIQ RLFAILMKML LDIEDDPVWH SAEEEHEDAG ETSNYSVGQE
CLDRLSISLG GNTIVPVASE LLPAYLAAPE WQKHHAALIA LAQIAEGCSK VMIKNLEQIV
SMVLNSFQDP HPRVRWAAIN AIGQLSTDLG PELQVKYHQR LLPALAAAMD DFQNPRVQAH
AASAVLNFSE NCTPDILTPY LDGIVSKLLV LLQNGKQMVQ EGALTALASV ADSSQVHFQK
YYDAVMPYLK AILVNANDKS NRMLRAKSME CISLVGMAVG KEKFRDDAKQ VMDVLMSLQG
SQMEADDPTT SYMLQAWARL CKCLGQDFLP YMNVVMPPLL QSAQLKPDVT ITSADSDADI
YDSDDDSIET ITLGDKRIGI KTSVLEEKAT ACNMLCCYAD ELKEGFFPWI DQVAPTLVPL
LKFYFHEEVR KAAVSAMPEL LRSAKLAVEK GQSQGRNESY IKQLSDYIIP ALVDALHKEP
ETEICASMLD SLNECIQISG PLLDEGQVRS IVDEIKQVIT ASSSRKRERA ERAKAEDFDA
EEGELLKEEN EQEEELFDQI GDCLGTLIKT FKSSFLPFFD ELSSYLMPMW GKDKTAEERR
IAICIFDDVA EQCRESALKY YDTYLPFLLE ACNDENPHVR QAAVYGIGVC AEFGGSAFKP
LVGEALSRLD VVIRHSNARD SDNVMAYDNA VSALGKICQF HRDSIDAVQI VPAWLSCLPL
KGDLIEAKVV HDQLCSMVER SDRELLGPNN QYLPKIVAVF AEVLCAGKDL ATEETTSRMI
NLLRQLRQTL SPSALASTWS SLQPQQQLAL QSILST
//
