ID F6HPR0_VITVI Unreviewed; 512 AA.
AC F6HPR0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Apyrase 6 {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=VIT_01s0026g02490 {ECO:0000313|EMBL:CCB56541.1};
OS Vitis vinifera (Grape).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; Vitales; Vitaceae; Viteae; Vitis.
OX NCBI_TaxID=29760 {ECO:0000313|EMBL:CCB56541.1, ECO:0000313|Proteomes:UP000009183};
RN [1] {ECO:0000313|Proteomes:UP000009183}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pinot noir / PN40024 {ECO:0000313|Proteomes:UP000009183};
RX PubMed=17721507; DOI=10.1038/nature06148;
RG The French-Italian Public Consortium for Grapevine Genome Characterization.;
RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A.,
RA Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F.,
RA Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J.,
RA Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E.,
RA Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M.,
RA Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M.,
RA Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E.,
RA Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M.,
RA Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G.,
RA Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F.,
RA Wincker P.;
RT "The grapevine genome sequence suggests ancestral hexaploidization in major
RT angiosperm phyla.";
RL Nature 449:463-467(2007).
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283}.
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DR EMBL; FN596002; CCB56541.1; -; Genomic_DNA.
DR AlphaFoldDB; F6HPR0; -.
DR STRING; 29760.F6HPR0; -.
DR PaxDb; 29760-VIT_01s0026g02490-t01; -.
DR EnsemblPlants; Vitvi01g01018_t001; Vitvi01g01018_P001; Vitvi01g01018.
DR Gramene; Vitvi01g01018_t001; Vitvi01g01018_P001; Vitvi01g01018.
DR eggNOG; KOG1386; Eukaryota.
DR HOGENOM; CLU_010246_5_1_1; -.
DR InParanoid; F6HPR0; -.
DR Proteomes; UP000009183; Chromosome 1.
DR ExpressionAtlas; F6HPR0; baseline and differential.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IBA:GO_Central.
DR GO; GO:0009134; P:nucleoside diphosphate catabolic process; IBA:GO_Central.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF3; APYRASE 6-RELATED; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000009183};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT ACT_SITE 184
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 214..218
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 512 AA; 56735 MW; 6E326B7C019E20EC CRC64;
MEQLKLQMRP NATARAQKNA TRSNLVVLIL LATVIAAFFL LLVLVCNSRN SMRRGKKYGI
VIDGGSTGTR IHVFGFELDG GGRPVFDFGK KGLGSMRVSP GLSSYAEDPN RAGGSLVELL
EFGKSRVPKE HWGDTEIRLM ATAGLRRLEL RVQEAILESC RRVLRVSSFQ FRDSWASVIT
GSDEGIYAWV VANHALGSLG GDPRETTGII ELGGASAQVT FVSSEPVPPE FSHTLRFGNV
TYNLYSHSLL DFGQNVALES LQKSLFSTDL MAAESLQKGI LIDPCTPKGY SLDGKNEYSS
AIHAQGNFSE CRAAALTLLQ KGKERCSYHH CLGSTFMPKL QGKFLATENF FYTSKFFGLG
SRAFLSDLTV AGQHFCEEDW SKLKRKYYSF NEEDLLHYCF SSAYIVAFLH DSLGIALDDE
RIGYANQVGD IPLDWALGAF ILQSTTNLEA EHSDWITTVV SDESPTLLSL VVILIILMFT
VWSISKCKKP QLKTIYDLEK GRYIVTRINR CS
//
