ID F6II60_9SPHN Unreviewed; 457 AA.
AC F6II60;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Major facilitator transporter {ECO:0000313|EMBL:CCA91502.1};
GN ORFNames=PP1Y_AT5335 {ECO:0000313|EMBL:CCA91502.1};
OS Novosphingobium sp. PP1Y.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Novosphingobium.
OX NCBI_TaxID=702113 {ECO:0000313|EMBL:CCA91502.1, ECO:0000313|Proteomes:UP000009242};
RN [1] {ECO:0000313|EMBL:CCA91502.1, ECO:0000313|Proteomes:UP000009242}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sp. PP1Y {ECO:0000313|Proteomes:UP000009242};
RX PubMed=21685292; DOI=10.1128/JB.05349-11;
RA D'Argenio V., Petrillo M., Cantiello P., Naso B., Cozzuto L., Notomista E.,
RA Paolella G., Di Donato A., Salvatore F.;
RT "De novo sequencing and assembly of the whole genome of Novosphingobium sp.
RT strain PP1Y.";
RL J. Bacteriol. 193:4296-4296(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FR856862; CCA91502.1; -; Genomic_DNA.
DR RefSeq; WP_013831943.1; NC_015580.1.
DR AlphaFoldDB; F6II60; -.
DR KEGG; npp:PP1Y_AT5335; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_001265_5_12_5; -.
DR OrthoDB; 7187764at2; -.
DR Proteomes; UP000009242; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR044770; MFS_spinster-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23505:SF79; SPHINGOLIPID TRANSPORTER SPINSTER HOMOLOG 2-RELATED; 1.
DR PANTHER; PTHR23505; SPINSTER; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009242};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 74..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..449
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 457 AA; 49022 MW; 3FFFBB27CEE60A69 CRC64;
MANPVPAQHD FQTDALPPDP LPERKAAWPA ARRSWMIATL LALASIASQF DRVVLNLTVE
PVKAHFGMDD TRFAMLQGVA FGIFYTICSV PIGRLADRHR RTGLLGISLL LFSVFSMASG
LARNFSQLFA SRVGVAVGEA SVTPTGLSLL ADLFPPQRLG RAVGVFFLSA PFGIGLAYLV
GGQLLDGLSA AHDTSGGLPL GLLPWQACFL LVSLPGLLLA PVFWLLREPA RRGTGHDRPM
TIAEVIKVVK DRRLALTLMF SGFSMVTVVN FAYNVWMPAL FGRVYGWDPA QVGLGFGLIM
IIFGTSGTFF AGVLADKVAA SGKVDAPLRV AAWSFLLCGI FGCVAPLMPN AWASLALIGP
TMFLSCMPVP CAGTALQLIV PNRARAQVTA LYIMIISLVG IGIGPMIIGF MNDHVFTGPT
DIRYSMAIVV GIASPLMWVL LLFALKPYRS LREAMDL
//
