ID F6IWG9_LACPE Unreviewed; 519 AA.
AC F6IWG9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 13-SEP-2023, entry version 51.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335};
GN ORFNames=LPE_02011 {ECO:0000313|EMBL:CCB82984.1};
OS Lactiplantibacillus pentosus MP-10.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactiplantibacillus.
OX NCBI_TaxID=1028490 {ECO:0000313|EMBL:CCB82984.1};
RN [1] {ECO:0000313|EMBL:CCB82984.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MP-10 {ECO:0000313|EMBL:CCB82984.1};
RX PubMed=21705590; DOI=10.1128/JB.05171-11;
RA Abriouel H., Benomar N., Perez Pulido R., Canamero M.M., Galvez A.;
RT "Annotated genome sequence of Lactobacillus pentosus MP-10, which has
RT probiotic potential, from naturally fermented Alorena green table olives.";
RL J. Bacteriol. 193:4559-4560(2011).
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_00335};
CC Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
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DR EMBL; FR871814; CCB82984.1; -; Genomic_DNA.
DR RefSeq; WP_050339349.1; NZ_FLYG01000003.1.
DR AlphaFoldDB; F6IWG9; -.
DR GeneID; 49394473; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00322; KH; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_00335}; Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00335};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_00335}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00335"
FT DOMAIN 335..428
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT COILED 69..138
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 519 AA; 58104 MW; D5E0F381C434A0BC CRC64;
MNVFGIILAV IAIVVGYGIG YYVRKNVHEK ELDVAKNTAE GIISEAKRAA ETHKKEKVLE
AKEESHRYRA EVETELKQRR NEVQKQEDRL LQREETLDHK ENTFEKREDA LGKKEEKVAN
EQKRVEQQQQ SAASLITQRQ AELERVAALS QEQARDQILT QTREQLTHER AVLIKENTDE
VKAQSEKEAK NLIVQAIQQS AADMVSETTV SVVSLPNDDM KGRIIGREGR NIRTLETLTG
IDLIIDDTPE AVVLSGYDPI RREIAKIALE KLIQDGRIHP ARIEEMVEKA RKEMDEKIRE
TGEQAVFDLG LHGMHPDLIK LVGRLNYRTS YGQNVLNHSI EVAKLAGVLA AELGEDVTLA
KRAGLLHDIG KAVDHEVEGS HVEIGVELTT KYKESPVVIN TIASHHGDVE AKSIIAVLVA
TSDSISAARP GARSESLENY IHRLEKLEAI ANEQAGVKKS YAIQAGREIR VIVKPNEISD
LQATVLAHDV KKQIENELEY PGHIKVTVIR EVRAVDYAK
//
