ID F6K356_ERISI Unreviewed; 1776 AA.
AC F6K356;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Myosin Va {ECO:0000313|EMBL:ADM15669.1};
OS Eriocheir sinensis (Chinese mitten crab).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Brachyura;
OC Eubrachyura; Grapsoidea; Varunidae; Eriocheir.
OX NCBI_TaxID=95602 {ECO:0000313|EMBL:ADM15669.1};
RN [1] {ECO:0000313|EMBL:ADM15669.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Testis {ECO:0000313|EMBL:ADM15669.1};
RX PubMed=22846366; DOI=10.1016/j.gene.2012.07.035;
RA Sun X., Mao H.T., Yang W.X.;
RT "Gene expression pattern of myosin Va during spermatogenesis of Chinese
RT mitten crab, Eriocheir sinensis.";
RL Gene 508:78-84(2012).
RN [2] {ECO:0000313|EMBL:AYV96979.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Hepatopancreas {ECO:0000313|EMBL:AYV96979.1};
RA Li H., Li P., Yan J., Xie W., Zhou K.;
RT "Identification, expression and function analysis of Myosin Va in the
RT Chinese mitten crab, Eriocheir sinensis.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; HM212671; ADM15669.1; -; mRNA.
DR EMBL; MG267059; AYV96979.1; -; mRNA.
DR SMR; F6K356; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd15470; Myo5_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140:SF860; DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C; 1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 4.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 6.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 2: Evidence at transcript level;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}.
FT DOMAIN 8..61
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 66..747
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1446..1727
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 626..648
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 899..1079
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1161..1219
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1252..1279
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1318..1352
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 160..167
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1776 AA; 203963 MW; 38F227052D09BB70 CRC64;
MSVRELYVRG AHVWIPDPAQ VWRCAELTQD YKGGSVTVIF EDGQTEKIKV KSDDDVPPLR
NPDILIGEND LTSLSYLHEP AVLYNLQVRF CNQNAIYTYC GIVLVAINPY EELPIYGPDT
ISAYRGHSMG DLDPHIFAVA EEAFTQMERD NRDQSIIVSG ESGAGKTVSA KYAMRYFASV
GGSDSETQIE KKILASNPIM EAIGNAKTTR NDNSSRFGKY IELDFASNYS IMGANMRTYL
LEKSRVVFQA PDERNYHIFY QLCSVASDGK FSTLDWGHQD NFHYLNQGSS PSIDGVDDAA
YFQETCKALS LLGITEARQE HMFRVLAGIL HLGNVTIEDS GGDASLINKN DESLPIVAKL
LGVSEADLRM WLCHRKITGG REVFNKPMTL REATFSRDAL AKHIYAKLFD WIVMQINKCF
AAPTKPFRFI GVLDIYGFET FEINSFEQFC INYANEKLQQ QFNQHVFKLE QEEYVKEQVE
WEFINFYDNQ PCIDLIESKL GILDLLDEEC RMPKGSDQSW VEKLYDKCKK WDHFSKPRLS
NSSFLIAHFA DKVGYECAGF LEKNRDTVSE EQINILKSSQ ISLIHSLFTE KAKGAPTKVK
VLPTAPSKAS SKQMKKSVGS QFRESLNLLM LTLNSTTPHY VRCIKPNDDK MAFTFDPTRA
IQQLRACGVL ETVRISAAGY PSRWTYPEFF CRYRVLCHSK DIVRNDMRMT CEKIIANMIN
DEDKFKFGRT KIFFRAGQVA YMEKLRADRL SACGIMIQKH VRMYLHRNRF RTMRRAAITI
QKYARGMAAR RRAQHMRETA AAIKIQACAR GWIKRVQYRR LVYIVTQLQA HARGAAARQR
YEHMRRVRAA IIIQKTVRKW LMRQRYLRAV RGLVAVQGLV RCYLARRQLK KLKIEAKSIE
HQKKLNKGLE NKIISLQHKL NEMKNENNAI AGYKDEIEVL KGRVTDLKTV EKQLKSSNNQ
IAELEAKVAK LTQEVETERG EKMDILTQKE RAEKENRELI EKLNEENAKL TLELSKVQVE
DVKRESEETL RRKFEAEKQQ LILETTDEKS GYQRLIKEFN RLEQRNEFLE EQLTKYKGGN
AHKRTASNVS NLSGVSDAPT ELVHDDTSEF PTFLGEDDVG YGSVRSRTSE VSDSSRNLES
IDWSSPSKVA SEIKLQVPEK LQELEMENAK LRDDLNRLRK SIADSEPQNN GVQEFMKQFE
ALQDELERRR EECIQLRTVL ANRAHDLRSV TQTSYGKDVD IVNEDGELVL AYQTQKQVNR
QLEDELRKQK LRAHETEAEY KGELDRLRQD NGRQQKLLAQ NLLKGDASNP EALLQSEIMR
LTSENLNLQG QVDSLTEQLK KYKRSLRAYA KKLKEAGGGD PPDLLDVAAT NEGEVMPVIR
KKERDYMGMF EYDRREEMQI IRVLVYELKP RLAVTLLPGL PAYILFMCIR HTDHINDDEK
VRSLLNNIVN GVKRVIKKRH EDPDSTVLWL SNVLRLLHNL KQYSGDKAFQ AENTVKQNEQ
SLKNFDLSEY RQVLSDIAVW IYNGVIKLME QKVQPLIVPS ILEHEAIAGL SGNKPGGMRG
RAGSLARELE SPVEPQKALD LLLKEMTQFY RALAMFGTDP ELITQVFRQI FYFICAGSLN
NLLLRKDMCH WSKGMQIRYN LSHLEQWTRD MRLHESGVTD TLAPIIQAAQ LLQARKTDDD
VHSICDMCDK LSVSQIIKIL NLYTPADDFE ERVPITFIHK IQAKLQERAE GEQAQATLLM
NTKFAFPVRF PFNPSSIHLE DIELPDALPL NMLKKV
//
