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Database: UniProt
Entry: F6PST8_ORNAN
LinkDB: F6PST8_ORNAN
Original site: F6PST8_ORNAN 
ID   F6PST8_ORNAN            Unreviewed;       695 AA.
AC   F6PST8;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   28-MAR-2018, entry version 34.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOANP00000023523};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000023523, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000023523}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000023523};
RX   PubMed=8919867; DOI=10.1007/BF02198841;
RA   Janke A., Gemmell N.J., Feldmaier-Fuchs G., von Haeseler A., Paabo S.;
RT   "The mitochondrial genome of a monotreme--the platypus
RT   (Ornithorhynchus anatinus).";
RL   J. Mol. Evol. 42:153-159(1996).
RN   [2] {ECO:0000313|Proteomes:UP000002279}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Proteomes:UP000002279};
RX   PubMed=18464734; DOI=10.1038/nature06936;
RA   Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E.,
RA   Ponting C.P., Grutzner F., Belov K., Miller W., Clarke L.,
RA   Chinwalla A.T., Yang S.P., Heger A., Locke D.P., Miethke P.,
RA   Waters P.D., Veyrunes F., Fulton L., Fulton B., Graves T., Wallis J.,
RA   Puente X.S., Lopez-Otin C., Ordonez G.R., Eichler E.E., Chen L.,
RA   Cheng Z., Deakin J.E., Alsop A., Thompson K., Kirby P.,
RA   Papenfuss A.T., Wakefield M.J., Olender T., Lancet D., Huttley G.A.,
RA   Smit A.F., Pask A., Temple-Smith P., Batzer M.A., Walker J.A.,
RA   Konkel M.K., Harris R.S., Whittington C.M., Wong E.S., Gemmell N.J.,
RA   Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J., Zemann A.,
RA   Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA   Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA   Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA   Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H.,
RA   Taylor J., Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y.,
RA   Huang X., Stark A., Kheradpour P., Kellis M., Flicek P., Chen Y.,
RA   Webber C., Hardison R., Nelson J., Hallsworth-Pepin K., Delehaunty K.,
RA   Markovic C., Minx P., Feng Y., Kremitzki C., Mitreva M., Glasscock J.,
RA   Wylie T., Wohldmann P., Thiru P., Nhan M.N., Pohl C.S., Smith S.M.,
RA   Hou S., Nefedov M., de Jong P.J., Renfree M.B., Mardis E.R.,
RA   Wilson R.K.;
RT   "Genome analysis of the platypus reveals unique signatures of
RT   evolution.";
RL   Nature 453:175-183(2008).
RN   [3] {ECO:0000313|Ensembl:ENSOANP00000023523}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000023523};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   STRING; 9258.ENSOANP00000023523; -.
DR   Ensembl; ENSOANT00000023527; ENSOANP00000023523; ENSOANG00000014942.
DR   eggNOG; KOG3703; Eukaryota.
DR   eggNOG; ENOG410XQN4; LUCA.
DR   GeneTree; ENSGT00760000119023; -.
DR   InParanoid; F6PST8; -.
DR   OMA; TVIHDLG; -.
DR   OrthoDB; EOG091G02CP; -.
DR   TreeFam; TF313193; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000014942; -.
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR021930; Heparan_SO4_deacetylase.
DR   InterPro; IPR037359; NST/OST.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR10605; PTHR10605; 1.
DR   Pfam; PF12062; HSNSD; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT   DOMAIN       12    328       HSNSD. {ECO:0000259|Pfam:PF12062}.
FT   DOMAIN      418    667       Sulfotransfer_1. {ECO:0000259|Pfam:
FT                                PF00685}.
SQ   SEQUENCE   695 AA;  80416 MW;  8FB0A3CB50372552 CRC64;
     EHLKMCFPFR LLKDGCINPY SPLLRVTKSS KLDKGPLPGS DWTVFPINHS SYQPVIFAKV
     KTPENLSPPI SKGALHATVV HDLGLHDRIQ RVLFGNNLNF WLHKLIFIDA VSFLSGKKLT
     LSLDRYILVD IDDIFVGKEG TRMNVRDVKA LLDTQNLLRA QITNFTFNLG FSGKFYHTGT
     EEEDEGDDLL LGSVDEFWWF PHMWSHMQPH LFQNESSLVE QMILNKKFAL EHGIPTDMGY
     AVAPHHSGVY PVHVQLYDAW KKVWNIRITS TEEYPHLKPA RHRRGFVHKN IMVLPRQTCG
     LFTHTIFYKE YPGGPKELDK SIQGGELFFT VILNPISIFM THLSNYGNDR LGLYTFVNLA
     NFVQSRTNLK LQTLPPVPLA RKYFELFPEQ KDPLWQNPCD DKRHRDIWSK EKTCDRLPKF
     LVIGPQKTGT TALYLFLVMH PSIISNSPSP KTFEEVQFFN RNNYHRGIDW YMEFFPTPSN
     ATTDFLFEKS ANYFHSEEAP KRAASLIPKA KIISILIDPS DRAYSWYQHQ RSHEDPAALK
     FSFYQVITAG SRAPSELRAL QKRCLVPGWY AAHIERWLNH FPPFQLLIID GQQLRTDPAT
     VMDEVQKFLG VSPHYNYSEA LTFDSHKGFW CQLLEEGKTK CLGKSKGRKY PPMDSECRAF
     LSNYYRDHNV ELSKLLHRLG QPLPSWLRQE LQKVS
//
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