ID F6Q2J4_HORSE Unreviewed; 393 AA.
AC F6Q2J4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Caspase recruitment domain family member 9 {ECO:0000313|Ensembl:ENSECAP00000008603.3};
GN Name=CARD9 {ECO:0000313|VGNC:VGNC:16055};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000008603.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000008603.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000008603.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000008603.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000008603.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6Q2J4; -.
DR STRING; 9796.ENSECAP00000008603; -.
DR PaxDb; 9796-ENSECAP00000008603; -.
DR Ensembl; ENSECAT00000011055.3; ENSECAP00000008603.3; ENSECAG00000019300.4.
DR VGNC; VGNC:16055; CARD9.
DR GeneTree; ENSGT00940000160570; -.
DR HOGENOM; CLU_093902_6_0_1; -.
DR InParanoid; F6Q2J4; -.
DR OMA; PGLRWLW; -.
DR OrthoDB; 3592839at2759; -.
DR TreeFam; TF313165; -.
DR Proteomes; UP000002281; Chromosome 25.
DR Bgee; ENSECAG00000010755; Expressed in articular cartilage of joint and 23 other cell types or tissues.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0051087; F:protein-folding chaperone binding; IBA:GO_Central.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0030150; P:protein import into mitochondrial matrix; IBA:GO_Central.
DR GO; GO:0050821; P:protein stabilization; IBA:GO_Central.
DR InterPro; IPR024158; Mt_import_TIM15.
DR InterPro; IPR003657; WRKY_dom.
DR InterPro; IPR007853; Znf_DNL-typ.
DR PANTHER; PTHR20922:SF13; DNL-TYPE ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR20922; UNCHARACTERIZED; 1.
DR Pfam; PF05180; zf-DNL; 1.
DR PROSITE; PS50811; WRKY; 1.
DR PROSITE; PS51501; ZF_DNL; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00834}.
FT DOMAIN 267..324
FT /note="WRKY"
FT /evidence="ECO:0000259|PROSITE:PS50811"
FT DOMAIN 279..376
FT /note="DNL-type"
FT /evidence="ECO:0000259|PROSITE:PS51501"
FT REGION 1..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..393
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..169
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 393 AA; 41464 MW; 6995B3BC41C1D962 CRC64;
MEKSRDSRLL STPTVRWPGR PGEPRGALCS PAKGAAFTDP QGRGQERRRA PGEGAAAPQG
ELRELPQEAR AQEDAARLET GGGGLGEHHG QRQHGHRGLL AGPWGRAAPP RPVLCPARSI
PLYCSPRRVL AIQLCNKRPR SVPAPPPPTA SSSALLPSPP AAPAHRPHRP PPGAAERGRP
AGAGSRGEPL PPRARVQDGG AAASAAGAGR GAGRGAGRQA PAGGMLRAAL RLVPTLWSHA
RPRGPDLRRL WGRGARPEAA GRRRAWGWDW RRWSSDPGPG AAHYQLVYTC KVCGTRSSKR
ISKLAYHQGV VIVTCPGCQN HHIIADNLGW FSDLDGKRNI EEILAARGEK VCRVASEGAL
ELVLEAAGAP KSTAAPEGDE DQDATHSGKT EPS
//
