ID F6Q9R1_HORSE Unreviewed; 436 AA.
AC F6Q9R1;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Perilipin {ECO:0000256|PIRNR:PIRNR036881};
GN Name=PLIN2 {ECO:0000313|Ensembl:ENSECAP00000022193.3,
GN ECO:0000313|VGNC:VGNC:21578};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000022193.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000022193.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000022193.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000022193.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000022193.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the perilipin family.
CC {ECO:0000256|ARBA:ARBA00006311, ECO:0000256|PIRNR:PIRNR036881}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; F6Q9R1; -.
DR Ensembl; ENSECAT00000026587.4; ENSECAP00000022193.3; ENSECAG00000024663.4.
DR VGNC; VGNC:21578; PLIN2.
DR GeneTree; ENSGT00950000182920; -.
DR HOGENOM; CLU_035133_0_1_1; -.
DR OMA; QENCHEA; -.
DR TreeFam; TF328397; -.
DR Proteomes; UP000002281; Chromosome 23.
DR Bgee; ENSECAG00000024663; Expressed in gluteus medius and 23 other cell types or tissues.
DR Gene3D; 1.20.120.340; Flagellar protein FliS; 2.
DR Gene3D; 3.30.720.170; Perilipin, alpha-beta domain; 1.
DR InterPro; IPR004279; Perilipin.
DR PANTHER; PTHR14024; PERILIPIN; 1.
DR PANTHER; PTHR14024:SF25; PERILIPIN-2; 1.
DR Pfam; PF03036; Perilipin; 1.
DR PIRSF; PIRSF036881; PAT; 1.
DR SUPFAM; SSF109775; Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT REGION 413..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 436 AA; 47708 MW; 729B8280284F0CD9 CRC64;
MASAAVDPQP SVVTRVANLP LVSSTYDLVS SAYISTKDQY PCLKSVCEMA EKGVKTITSV
AVSSALPLIQ KLEPQIALAN TYACKGLDRI EEKLPILNQP TNQVVANARG AMNGAKDAVT
TTVTGAKDSV ASTITGVMDR TKGAVTGSVE KTKSVVNGSI NTVLGSRMVQ LVSSGVENAL
TRSELLVDQY LPLTEEELEK EAKKVEGFDP MQKPSYYIRL GSLSSKLRSR AYQQALSRVK
EVKQRSQATI SQLHSTVNLI EFARNNVHSA NQKIQDAQDK LYLSWVEWKR NIGHDDTDES
HCAEHIESRT LAIARNLTQQ LQTTCHTLLC SVQGLPQNIQ DQASHLGVMA GDIYSVFHNA
ASFQEVSEGL LTSSKGQLQK MKESLDDVMD YLVNNTPLNW LVGPFYPQLT ESQNAQNKGT
EDTASQETQQ PEHKTH
//
