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Database: UniProt
Entry: F6QBE8_ORNAN
LinkDB: F6QBE8_ORNAN
Original site: F6QBE8_ORNAN 
ID   F6QBE8_ORNAN            Unreviewed;       718 AA.
AC   F6QBE8;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   28-MAR-2018, entry version 36.
DE   SubName: Full=MTSS1L, I-BAR domain containing {ECO:0000313|Ensembl:ENSOANP00000001855};
GN   Name=MTSS1L {ECO:0000313|Ensembl:ENSOANP00000001855};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000001855, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000001855}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000001855};
RX   PubMed=8919867; DOI=10.1007/BF02198841;
RA   Janke A., Gemmell N.J., Feldmaier-Fuchs G., von Haeseler A., Paabo S.;
RT   "The mitochondrial genome of a monotreme--the platypus
RT   (Ornithorhynchus anatinus).";
RL   J. Mol. Evol. 42:153-159(1996).
RN   [2] {ECO:0000313|Proteomes:UP000002279}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Proteomes:UP000002279};
RX   PubMed=18464734; DOI=10.1038/nature06936;
RA   Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E.,
RA   Ponting C.P., Grutzner F., Belov K., Miller W., Clarke L.,
RA   Chinwalla A.T., Yang S.P., Heger A., Locke D.P., Miethke P.,
RA   Waters P.D., Veyrunes F., Fulton L., Fulton B., Graves T., Wallis J.,
RA   Puente X.S., Lopez-Otin C., Ordonez G.R., Eichler E.E., Chen L.,
RA   Cheng Z., Deakin J.E., Alsop A., Thompson K., Kirby P.,
RA   Papenfuss A.T., Wakefield M.J., Olender T., Lancet D., Huttley G.A.,
RA   Smit A.F., Pask A., Temple-Smith P., Batzer M.A., Walker J.A.,
RA   Konkel M.K., Harris R.S., Whittington C.M., Wong E.S., Gemmell N.J.,
RA   Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J., Zemann A.,
RA   Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA   Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA   Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA   Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H.,
RA   Taylor J., Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y.,
RA   Huang X., Stark A., Kheradpour P., Kellis M., Flicek P., Chen Y.,
RA   Webber C., Hardison R., Nelson J., Hallsworth-Pepin K., Delehaunty K.,
RA   Markovic C., Minx P., Feng Y., Kremitzki C., Mitreva M., Glasscock J.,
RA   Wylie T., Wohldmann P., Thiru P., Nhan M.N., Pohl C.S., Smith S.M.,
RA   Hou S., Nefedov M., de Jong P.J., Renfree M.B., Mardis E.R.,
RA   Wilson R.K.;
RT   "Genome analysis of the platypus reveals unique signatures of
RT   evolution.";
RL   Nature 453:175-183(2008).
RN   [3] {ECO:0000313|Ensembl:ENSOANP00000001855}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000001855};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   STRING; 9258.ENSOANP00000001855; -.
DR   Ensembl; ENSOANT00000001856; ENSOANP00000001855; ENSOANG00000001163.
DR   eggNOG; ENOG410IGVU; Eukaryota.
DR   eggNOG; ENOG410XRT4; LUCA.
DR   GeneTree; ENSGT00390000002637; -.
DR   InParanoid; F6QBE8; -.
DR   OrthoDB; EOG091G083M; -.
DR   TreeFam; TF320619; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000001163; -.
DR   GO; GO:0030864; C:cortical actin cytoskeleton; IEA:Ensembl.
DR   GO; GO:0030027; C:lamellipodium; IEA:Ensembl.
DR   GO; GO:0032587; C:ruffle membrane; IEA:Ensembl.
DR   GO; GO:0003785; F:actin monomer binding; IEA:Ensembl.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:Ensembl.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR   GO; GO:0048365; F:Rac GTPase binding; IEA:Ensembl.
DR   GO; GO:0090630; P:activation of GTPase activity; IEA:Ensembl.
DR   GO; GO:0036120; P:cellular response to platelet-derived growth factor stimulus; IEA:Ensembl.
DR   GO; GO:0097581; P:lamellipodium organization; IEA:Ensembl.
DR   GO; GO:0007009; P:plasma membrane organization; IEA:InterPro.
DR   GO; GO:0097178; P:ruffle assembly; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   InterPro; IPR030059; ABBA.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR013606; I-BAR_dom.
DR   InterPro; IPR030127; MIM/ABBA.
DR   PANTHER; PTHR15708; PTHR15708; 1.
DR   PANTHER; PTHR15708:SF8; PTHR15708:SF8; 1.
DR   Pfam; PF08397; IMD; 1.
DR   SUPFAM; SSF103657; SSF103657; 1.
DR   PROSITE; PS51338; IMD; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT   DOMAIN        1    252       IMD. {ECO:0000259|PROSITE:PS51338}.
FT   COILED      104    124       {ECO:0000256|SAM:Coils}.
FT   COILED      164    184       {ECO:0000256|SAM:Coils}.
FT   COILED      642    662       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   718 AA;  77696 MW;  9E6AC3F19211BE7A CRC64;
     METVDKECGA LGGLFQAIVN DMKSSYPIWE DFNSKATKLH SQLRTTVLAA VAFLDAFQKV
     ADMATNTRGA TRDIGSALTR MCMRHRSIEA KLRQFTNALL ESLINPLQER IEDWKKTANQ
     LDKDHAKEYK RARHEIKKKS SDTLKLQKKA RKELLGKGDL QPQLDNALQD VNDMYLLLEE
     TEKQAVRRAL IEERGRFCTF ITFLQPVVNG EITMLGEITH LQGIIEDLVV LTAEPHKLPP
     ASEQVIKDLK GSDYSWSYQT PPSSPSSSGS RKSSMCSHPS SVNSTKGGTP WPGGSQTYSP
     SSTYRYRSLA QPVNTNTRLS SVSSHDSGFI SQDAAYSKPP SPMPSDITSQ KSSSSASSEA
     SETCQSVSEC SSPTSDWSKA GPYDQSTVTT LQRRKDRVEH LREAELGPAG AGYPGAGGDD
     SPRPRMSPAT IAAKHGEEVS PAASDLAMVL TRGLSLEHQK SSRDSLQYSS GYSTQTTTPS
     CSEDTIPSQG SDYDCYSVNG GRGGARATAE FQYLIHHSRA TNIXQNNRRM IQTKRPASVA
     TIRRTPSTKP SVRRALSSAG PIPIRPPIVP VKTPTVPDSP GSGGGPVRVG SEECVFYATD
     ASPHAPDFLK GSPKRLSLPN ASWGGAAPEA AGYPGGGPSL SAEEEEEEQQ QLAANRHSLV
     EKIGELVAGA HALGEGQFPF PTALSATPGE EEDMLVAIRR GVRLRRTVTN DRSAPRLS
//
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