ID F6QLE7_XENTR Unreviewed; 1171 AA.
AC F6QLE7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Protein WWC2 {ECO:0000313|Ensembl:ENSXETP00000030868};
GN Name=wwc2 {ECO:0000313|Ensembl:ENSXETP00000030868};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000030868};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000030868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000030868};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000030868}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
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DR AlphaFoldDB; F6QLE7; -.
DR Ensembl; ENSXETT00000030868; ENSXETP00000030868; ENSXETG00000025753.
DR AGR; Xenbase:XB-GENE-1001637; -.
DR Xenbase; XB-GENE-1001637; wwc2.
DR HOGENOM; CLU_005420_0_0_1; -.
DR TreeFam; TF324040; -.
DR Bgee; ENSXETG00000025753; Expressed in neurula embryo and 15 other cell types or tissues.
DR CDD; cd08680; C2_Kibra; 1.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037771; C2_WWC.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR14791; BOMB/KIRA PROTEINS; 1.
DR PANTHER; PTHR14791:SF26; PROTEIN WWC2; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}.
FT DOMAIN 9..42
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 56..89
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 684..806
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 521..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 304..418
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 838..865
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1059..1122
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1171 AA; 132459 MW; F3D277FCE4512B56 CRC64;
MPRKGNGQLP LPDGWEEARD YDGKVFYIDH NSRQTSWIDP RDRLTKPLSF ADCVGNELPW
GWESSYDPQI GVYFINHINQ TTQIEDPRKL WRNEQERMLK DYLMVAQDAL STQKELYHIK
EQRLALALDE YVRLNDAYKE KSSSRTSLFS GSSSSTKYDP DILKAEISTT KVRVKKLKRE
LSQMKQELLY KEQGFETLQR IDQKMSGGQS GYELREAKDI LSELKSIRKA ISTGEKEKQD
LMQSLVKLKE RFHLEEARGR SEPDLRSNLA NSHLSLSRQT LDAGSQTDIS GDIGVRSRSN
LAEKVRLSLQ YEEAKRSMAN LKIELAKLDS EAWPGALDVE KEKLMLINEK EELLKELQFV
TTRRRTQGEI ERLEGERRRL EEELLSVKSS PSKALAERLK IQEKKKELVK KLEEVTKSAT
YLHSQLKSLS ASTLSVSSGS SIGSLASSRG SLNTSSRGSL NSLSSTDLYY NQNEPAADLD
YQYKLDFLLQ EKSGYIPCGP ITTIHENEVV HCHERIDYTN SPTAQQDTQD AKPPKSVTSL
SSLSSLSSLS PPGSPPVLEG VFSLCTQDSL RTGFEISELP ESFADMNLHE NLQLMESVAG
ESQALAERKS TGEGLRHQSS ASQEGRTDIE FPRKNPDRVQ EEKAMCVSAA VSDESVAGDS
GVYEPSVKPP GEDPVFNDDY SILGAAQAQL ILRYDSGNSS FVIIIVKARN NLSYVQFGSR
IYFRVAVLPS SNDTSCLFRT KVYPATESVL FNELFRVSIS QTTLQQKTLR VDMCSVGKTH
REDCLAGTQI SLADFSFSND VHTQWYTLLP SRTIPLYKEQ LEKSVLSASN TQTAALDLDA
VSALLERTSA ELEAVEQELA QEDDDQEQLC PGDDWPEMAP EESFSTLEEH EADLLLSGEY
YAVPLQLSSE TTEKSEELYG ETSNWDSVVS PLPQAELPTL VDKETNTEEA LQENLSVRPK
ERANLGSRQR PFVRNSMIVR SQTFSPGEKN QYICRLNRSD SDSSTLAKKS PFIRNANERR
SLRVKRPICQ PMTRRTVHEC RERTSLDLEL DLQASLTRQS RLNDELQSLR DLKQRLEEMK
ARGETELPLC VLEDERFQRL LKQAEKQAEQ SKEEQKQGLN AEKLMRKASK DVCRLREQSQ
KVPLQVQSFR EKITYFTRAK ISIPSLSADD V
//
