ID F6RY17_HORSE Unreviewed; 696 AA.
AC F6RY17;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=SEC14 like lipid binding 5 {ECO:0000313|Ensembl:ENSECAP00000010171.2};
GN Name=SEC14L5 {ECO:0000313|Ensembl:ENSECAP00000010171.2,
GN ECO:0000313|VGNC:VGNC:22785};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000010171.2, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000010171.2, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000010171.2,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000010171.2}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000010171.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6RY17; -.
DR SMR; F6RY17; -.
DR STRING; 9796.ENSECAP00000010171; -.
DR PaxDb; 9796-ENSECAP00000010171; -.
DR Ensembl; ENSECAT00000012870.4; ENSECAP00000010171.2; ENSECAG00000012311.4.
DR VGNC; VGNC:22785; SEC14L5.
DR GeneTree; ENSGT00940000160832; -.
DR HOGENOM; CLU_023840_0_0_1; -.
DR InParanoid; F6RY17; -.
DR OMA; YHTKQVP; -.
DR OrthoDB; 6048at2759; -.
DR TreeFam; TF313988; -.
DR Proteomes; UP000002281; Chromosome 13.
DR Bgee; ENSECAG00000012311; Expressed in spinal cord and 10 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011074; CRAL/TRIO_N_dom.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR006797; PRELI/MSF1_dom.
DR PANTHER; PTHR23324; SEC14 RELATED PROTEIN; 1.
DR PANTHER; PTHR23324:SF39; SEC14-LIKE PROTEIN 5; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF03765; CRAL_TRIO_N; 1.
DR Pfam; PF04707; PRELI; 1.
DR PRINTS; PR00180; CRETINALDHBP.
DR SMART; SM01100; CRAL_TRIO_N; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50866; GOLD; 1.
DR PROSITE; PS50904; PRELI_MSF1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 3..175
FT /note="PRELI/MSF1"
FT /evidence="ECO:0000259|PROSITE:PS50904"
FT DOMAIN 306..482
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 509..653
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
FT REGION 186..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 696 AA; 78731 MW; 7389F89B4407464A CRC64;
MVQKYQSPIR IYKYPFELVM AAYERRFPTC PEIPVLLGSQ VLREARSADG AVHVVERSCR
LRVEAPRLLR KIAGVEHVVF VQRNVLNWRE RTLLIDAHNE TFASRVVVRE NCSYTVHPEN
EDWTCFEQSA SLDIRSFFGF ESALEKIAMK QYTANVKRGK EVIEHYLHEL VSQGISHIPR
WTPAPVREED ARAQAGPRDP GSLEVGGPSN PPTPAPETVG LDGDKLDADY IERRLGHLTP
VQESCLIQLR QWLQENHKGK IPKDQHILRF LRARDFHLDK AREMLCQSLS WRKQHQVDLL
CQTWRPPAVL EEFYAGGWHY QDVDGRPLYI LRLGHMDTKG LMKAVGEEAL LWHVLSVNEE
GQKRCEGNTK QFGRPISSWT CLVDLEGLNM RHLWRPGVKA LLQMIEVVEA NYPETLGRLL
IVRAPRVFPV LWTLISPFIN ENTRQKFLIY SGSNYQGPGG LVDYLEEEVI PDFLGGECLC
NVPEGGLVPK SLYLTDEAQE HADQLRQWRD TYQSASVLRG APHEVEVEIL EGESVITWDF
DILRGDVVFS LYYTKRAARP GPREPGARAG GQLTDKGWVL GSEYSRVEAP LVCREGESIQ
GSHVTRWPGV YLLQWQMHGP PSHVACSLPG MEDVLTALHS PGARCKLLYY YEVLASEDFR
GSMSSLASCT SRFSQLSAAT SSSSSGQSHS GSLVSR
//
