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Database: UniProt
Entry: F6SP61_CIOIN
LinkDB: F6SP61_CIOIN
Original site: F6SP61_CIOIN 
ID   F6SP61_CIOIN            Unreviewed;       414 AA.
AC   F6SP61;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   18-APR-2012, sequence version 2.
DT   07-JUN-2017, entry version 49.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCINP00000022059};
GN   Name=LOC101243493 {ECO:0000313|Ensembl:ENSCINP00000022059};
OS   Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona;
OC   Phlebobranchia; Cionidae; Ciona.
OX   NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000022059, ECO:0000313|Proteomes:UP000008144};
RN   [1] {ECO:0000313|Ensembl:ENSCINP00000022059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15114417; DOI=10.1007/s00239-003-2559-6;
RA   Gissi C., Iannelli F., Pesole G.;
RT   "Complete mtDNA of Ciona intestinalis reveals extensive gene
RT   rearrangement and the presence of an atp8 and an extra trnM gene in
RT   ascidians.";
RL   J. Mol. Evol. 58:376-389(2004).
RN   [2] {ECO:0000313|Ensembl:ENSCINP00000022059}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCINP00000022059}.
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DR   EMBL; EAAA01001387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_004225692.1; XM_004225644.2.
DR   ProteinModelPortal; F6SP61; -.
DR   STRING; 7719.ENSCINP00000022059; -.
DR   Ensembl; ENSCINT00000022305; ENSCINP00000022059; ENSCING00000011580.
DR   GeneID; 101243493; -.
DR   KEGG; cin:101243493; -.
DR   eggNOG; ENOG410IF9A; Eukaryota.
DR   eggNOG; ENOG4111SVN; LUCA.
DR   GeneTree; ENSGT00760000119325; -.
DR   InParanoid; F6SP61; -.
DR   KO; K16891; -.
DR   OMA; YWKDGYN; -.
DR   OrthoDB; EOG091G0D3H; -.
DR   TreeFam; TF343841; -.
DR   Proteomes; UP000008144; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005261; F:cation channel activity; IBA:GO_Central.
DR   GO; GO:0006816; P:calcium ion transport; IBA:GO_Central.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008144};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     66     84       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     96    118       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    201    224       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    269    292       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       65    300       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   414 AA;  48113 MW;  C5865875CE8DB6FF CRC64;
     MEKKSRRGAV ISHNEGVADG RDNSPYMADN DVESEENEWE EEPGCESWRK DKAIHELAQK
     ISESEVFNGL IMAAIFANSI IMMLDVNNYY PSMKPYFPAA DIAFLAIYSI EFVVKIYAEP
     IQYWTTWSNR FDFFILLISY MQVLVDQFFA DASKEASWTG ALPMLRTLKA TRALRAMRAV
     SFVRGLQVLL TALIDTMKKS FINVMLILLF VMFLFAIFGY YMFGYKGGDE ENWGDLGSAF
     LTLFSFVTVD GWFDAQIEMD ERTTPSSRIY TILFIICGHF LIFNIFVGVN IMNIQEANEN
     YHEQVIAEKE AILARKKESI LHRQHEDVRK LKEKQKEKDC GNFYEMVKSF QESLHNDDYV
     IQEDLITNLD WMELYIETLA HMDEGVVKIR QYHYEISHIL TQAFSKEISK RLGE
//
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