ID F6T9K7_XENTR Unreviewed; 180 AA.
AC F6T9K7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Chromobox 3 {ECO:0000313|Ensembl:ENSXETP00000026572};
DE SubName: Full=Chromobox protein homolog 3 isoform X3 {ECO:0000313|RefSeq:XP_031759012.1};
GN Name=cbx3 {ECO:0000313|Ensembl:ENSXETP00000026572,
GN ECO:0000313|RefSeq:XP_031759012.1,
GN ECO:0000313|Xenbase:XB-GENE-492315};
GN Synonyms=cbx3-a {ECO:0000313|RefSeq:XP_031759012.1}, cbx3-b
GN {ECO:0000313|RefSeq:XP_031759012.1}, hech
GN {ECO:0000313|RefSeq:XP_031759012.1}, hp1-gamma
GN {ECO:0000313|RefSeq:XP_031759012.1}, hp1hs-gamma
GN {ECO:0000313|RefSeq:XP_031759012.1}, xhp1g
GN {ECO:0000313|RefSeq:XP_031759012.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000026572};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000026572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000026572};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000026572}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_031759012.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_031759012.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_031759012.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_017949991.1; XM_018094502.1.
DR RefSeq; XP_031759012.1; XM_031903152.1.
DR STRING; 8364.ENSXETP00000026572; -.
DR Ensembl; ENSXETT00000026572; ENSXETP00000026572; ENSXETG00000012175.
DR AGR; Xenbase:XB-GENE-492315; -.
DR Xenbase; XB-GENE-492315; cbx3.
DR eggNOG; KOG1911; Eukaryota.
DR HOGENOM; CLU_045874_1_2_1; -.
DR OrthoDB; 75895at2759; -.
DR TreeFam; TF350503; -.
DR Proteomes; UP000008143; Chromosome 6.
DR Bgee; ENSXETG00000012175; Expressed in gastrula and 16 other cell types or tissues.
DR GO; GO:0000792; C:heterochromatin; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR CDD; cd18652; CD_HP1gamma_Cbx3; 1.
DR CDD; cd18654; CSD_HP1beta_Cbx1; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR InterPro; IPR038033; CBX3_chromo_domain.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR017984; Chromo_dom_subgr.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR008251; Chromo_shadow_dom.
DR InterPro; IPR023779; Chromodomain_CS.
DR PANTHER; PTHR22812; CHROMOBOX PROTEIN; 1.
DR PANTHER; PTHR22812:SF134; CHROMOBOX PROTEIN HOMOLOG 3; 1.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF01393; Chromo_shadow; 1.
DR PRINTS; PR00504; CHROMODOMAIN.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00300; ChSh; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR PROSITE; PS00598; CHROMO_1; 1.
DR PROSITE; PS50013; CHROMO_2; 2.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 26..84
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 118..176
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 74..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 180 AA; 20692 MW; E23C600B75C32162 CRC64;
MEQRWTMGKK QNGKGKKVEE AEPEEFVVEK VLDRRVVNGK VEYYLKWKGF TDSDNTWEPE
ENLDCPELIE AFLNSQKAGK EKPDSNKRKS VSDSESEDSK SKKKRETVDK PRGFARGLDP
ERIIGATDSS GELMFLMKWK DSDEADLVPA KEANVKCPQV VIAFYEERLT WHSCPEDEAQ
//
