ID F6TGM0_HORSE Unreviewed; 451 AA.
AC F6TGM0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Ig-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=LOC111775265 {ECO:0000313|Ensembl:ENSECAP00000006716.3};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000006716.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000006716.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000006716.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000006716.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000006716.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6TGM0; -.
DR PaxDb; 9796-ENSECAP00000006716; -.
DR Ensembl; ENSECAT00000008908.3; ENSECAP00000006716.3; ENSECAG00000008745.4.
DR GeneTree; ENSGT01100000263478; -.
DR HOGENOM; CLU_021100_2_0_1; -.
DR InParanoid; F6TGM0; -.
DR OMA; HMESEPR; -.
DR TreeFam; TF336644; -.
DR Proteomes; UP000002281; Chromosome 10.
DR Bgee; ENSECAG00000008745; Expressed in leukocyte and 8 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11738:SF88; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11738; MHC CLASS I NK CELL RECEPTOR; 1.
DR Pfam; PF00047; ig; 2.
DR Pfam; PF13895; Ig_2; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..451
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040158468"
FT DOMAIN 40..124
FT /note="Immunoglobulin subtype"
FT /evidence="ECO:0000259|SMART:SM00409"
FT DOMAIN 45..113
FT /note="Immunoglobulin subtype 2"
FT /evidence="ECO:0000259|SMART:SM00408"
FT DOMAIN 135..224
FT /note="Immunoglobulin subtype"
FT /evidence="ECO:0000259|SMART:SM00409"
FT DOMAIN 235..316
FT /note="Immunoglobulin subtype"
FT /evidence="ECO:0000259|SMART:SM00409"
FT DOMAIN 241..303
FT /note="Immunoglobulin subtype 2"
FT /evidence="ECO:0000259|SMART:SM00408"
FT DOMAIN 329..409
FT /note="Immunoglobulin subtype"
FT /evidence="ECO:0000259|SMART:SM00409"
FT DOMAIN 335..402
FT /note="Immunoglobulin subtype 2"
FT /evidence="ECO:0000259|SMART:SM00408"
SQ SEQUENCE 451 AA; 49600 MW; 9FCDA97EEDB92114 CRC64;
MGGSIRNATL SALLCLALCR GLWNQVQAGV TPKPSIWADP GPVVTWGSPV TIWCQGSLQA
DVYHLYREEV YSPVGIKAPQ DSSNKTSFSI ESVSSQTAGL YQCAYHIRRN SWSERSDQLR
LVVTGMYSAP SLSAHPSPVA ASGVNVSLLC SSKNTFGTFH LLKEGGADPP RHVESRIHHW
REPAVFPVGP VNTSHGGTYR CYYNPHSYPY VWSHPSGPLH LEVTGVYREP SLSAHPGSLV
LSGDNLTLQC RSEAGFDRFA LTKDEGLTPP EHLHGRHSPD FPLGHVNHTN GGQYRCYGGH
NLSHVWSAPS APLDILIMGM YKKPSLSAQP GPSVSWGENV TLRCRSEIWF DTFHLSKEGS
PAPPQLLHLQ DTAAPFQANF TIGPVTSDHE ATYRCYGSDS TSPHLLSLPS DPLELQISGC
RWLQRQRLRT KACRRAPAHL LRSKRRTCML S
//
