ID F6TN13_MOUSE Unreviewed; 463 AA.
AC F6TN13;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=RNA-binding region-containing protein 3 {ECO:0000256|ARBA:ARBA00020364};
DE Flags: Fragment;
GN Name=Rnpc3 {ECO:0000313|Ensembl:ENSMUSP00000115492.2,
GN ECO:0000313|MGI:MGI:1914475};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000115492.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000115492.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115492.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000115492.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000115492.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR jPOST; F6TN13; -.
DR MaxQB; F6TN13; -.
DR PeptideAtlas; F6TN13; -.
DR ProteomicsDB; 348906; -.
DR Antibodypedia; 9690; 101 antibodies from 23 providers.
DR Ensembl; ENSMUST00000153853.8; ENSMUSP00000115492.2; ENSMUSG00000027981.15.
DR AGR; MGI:1914475; -.
DR MGI; MGI:1914475; Rnpc3.
DR VEuPathDB; HostDB:ENSMUSG00000027981; -.
DR GeneTree; ENSGT00530000063786; -.
DR HOGENOM; CLU_039888_2_1_1; -.
DR ChiTaRS; Rnpc3; mouse.
DR Proteomes; UP000000589; Chromosome 3.
DR Bgee; ENSMUSG00000027981; Expressed in retinal neural layer and 272 other cell types or tissues.
DR ExpressionAtlas; F6TN13; baseline and differential.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12239; RRM2_RBM40_like; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 6.10.250.610; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR045164; RBM41/RNPC3.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR16105:SF6; RNA-BINDING REGION-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR16105; UNCHARACTERIZED; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:F6TN13,
KW ECO:0007829|MaxQB:F6TN13};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 1..51
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 367..450
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 56..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..178
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..195
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000115492.2"
SQ SEQUENCE 463 AA; 52587 MW; 162D4D9489A52945 CRC64;
XQSVRVLSDK GRLKHTAFAT FPNEKAAIKA LTRLHQLKLL GHTLVVEFAK EQDRVHSPCS
TSNTEKKKRL DDTVENDKEK KEPDILTVEN GIAPNHGLTF PLNSCLKYMY PPPSSTILAN
IVNALASVPK FYVQVLHLMN KMNLPTPFGP ITARPPMYED YMPLHAPLPP TSPQPPEEPP
LPDEDEDLSS KESEYESSDE EDRQRMNRLM ELANLQPKRP KTEKPRHVRK KRKIKDMLNI
PSSASHSLHP VLLPSDVFDQ PQSVGNKKIE FNISTNMPAA FNKDLETQPN NEEENSDSPD
TGLDSNTGFG KIFPKPNLNI TEEITEDSDE IPSQFISRKE LEKGRISREE METLSVFRSY
EPGEPNCRIY VKNLARHVQE KDLKFIFGRY VDFSSETQRI MFDIRLMKEG RMKGQAFVGL
PNEKAAAKAL KEANGYVLFG KPMVVQFARS ARPKQDSKEG KRK
//
