ID F6TXZ0_CIOIN Unreviewed; 1047 AA.
AC F6TXZ0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCINP00000010301.3};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000010301.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000010301.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; EAAA01001639; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F6TXZ0; -.
DR STRING; 7719.ENSCINP00000010301; -.
DR Ensembl; ENSCINT00000010301.3; ENSCINP00000010301.3; ENSCING00000005010.3.
DR GeneTree; ENSGT00940000156118; -.
DR HOGENOM; CLU_006750_1_0_1; -.
DR InParanoid; F6TXZ0; -.
DR OMA; PLFIRVE; -.
DR TreeFam; TF317264; -.
DR Proteomes; UP000008144; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013806; Kringle-like.
DR PANTHER; PTHR47143:SF1; PWWP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47143; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS; 1.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF13637; Ank_4; 2.
DR Pfam; PF00040; fn2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 16.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 9.
DR PROSITE; PS50088; ANK_REPEAT; 9.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 748..771
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 884..902
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 922..944
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 956..975
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 995..1019
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 41..73
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 122..155
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 156..188
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 256..288
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 289..321
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 322..354
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 404..436
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 471..503
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 537..569
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 840..872
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|Pfam:PF00040"
FT DOMAIN 888..1025
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
SQ SEQUENCE 1047 AA; 118451 MW; 87A985A6CD0039E1 CRC64;
DNISSNLQLA RDGETDTLNK MLQSIPEIQR RRLVNASTDD EGATALHLAA RHNHYNVCEL
LINSGSNVDA RGEGRATPLH FAARYKHKQK RSTDDPYVNE QTKGVIALLA ERGAHINFVD
IEGQTPLHSA SIKGNLHAVR QLLKCRGCGI DNTDSQGMTA LQMAATHGHV EIVQLLLEQG
ADFQMYDNDL MTALHFACSE GSIDIVRKMM MRPDAGKNTC LHVTVNKGHR DLTLELIAWS
GKLDEVLQFV NLPRAHNVTP LHIAASQGHM EITKLLIESG ARVNARNDSL ATPLLLAAQH
NNFAIVELLL QYNAELEIRD KDNLTPLLIV CKQGHLETIS WLVENNADVT ATDKNDKNCL
MLAVEDKRTS AVQTFFGHTR TKPPSLELLR YEAVRKLLEE TDKNANSVLH LAAKKGFLPI
IRILLEHDAR IDPKNEDEST PVHIAAAHGQ HMALKELLDH DKTMINSLDE NANTALHLSA
IEGHTTCIEV LLDHGANVGL RNTKQWTALD CACSKGFELT VQKLLQAQSP LNPLRGARTT
PLHQACVNGH VHVVKILLDW RADVSYRLVD GRNPLDCAID ADKRECVQAI IQHSSWKNAM
RNGYTDPLTD LIVTPVRKLI VKMPDMAELA FSRCITDNKK PPDDLSLEVK LDYEFLDDMY
TVIQWNDSHH NDHDDDSGKK PVIPETGYEA FNDHGKLTKS AITYTEDTSV LRHNHPLSIM
VNRKRERLLQ HPVVTALLQY KWKKYGGLVY YSSLIFLMLF VGLLNCYLIF IPPPYSIDYL
KSLGNRRFYG EFTADHINNY TVTALIQQLI VQITEPCIFT VTQMQLYVPE KHAMLLHAQK
GAEFTECLIH STGGIWCAYT YDFDTDVKWG YCSEETGLRQ NWQWQCGVMA LFLSWMNLLL
YIRKIPYLGI YVVMFNDVFK TFVKFSLVFL LFILSFAFTF HTLLQNEPQF EQSFNAILKT
TVMMVGEIDF GGIFFGDQVS FSNQVFYKEV TYLVFSIFII VMMIIVMNLL VGLAVGDIIE
VKEHATLERL KMQVELALEV EFRIHNF
//
