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Database: UniProt
Entry: F6U8Z0_ORNAN
LinkDB: F6U8Z0_ORNAN
Original site: F6U8Z0_ORNAN 
ID   F6U8Z0_ORNAN            Unreviewed;       515 AA.
AC   F6U8Z0;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   05-JUL-2017, entry version 46.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOANP00000016505};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000016505, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000016505, ECO:0000313|Proteomes:UP000002279}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000016505,
RC   ECO:0000313|Proteomes:UP000002279};
RX   PubMed=18464734; DOI=10.1038/nature06936;
RA   Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E.,
RA   Ponting C.P., Grutzner F., Belov K., Miller W., Clarke L.,
RA   Chinwalla A.T., Yang S.P., Heger A., Locke D.P., Miethke P.,
RA   Waters P.D., Veyrunes F., Fulton L., Fulton B., Graves T., Wallis J.,
RA   Puente X.S., Lopez-Otin C., Ordonez G.R., Eichler E.E., Chen L.,
RA   Cheng Z., Deakin J.E., Alsop A., Thompson K., Kirby P.,
RA   Papenfuss A.T., Wakefield M.J., Olender T., Lancet D., Huttley G.A.,
RA   Smit A.F., Pask A., Temple-Smith P., Batzer M.A., Walker J.A.,
RA   Konkel M.K., Harris R.S., Whittington C.M., Wong E.S., Gemmell N.J.,
RA   Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J., Zemann A.,
RA   Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA   Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA   Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA   Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H.,
RA   Taylor J., Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y.,
RA   Huang X., Stark A., Kheradpour P., Kellis M., Flicek P., Chen Y.,
RA   Webber C., Hardison R., Nelson J., Hallsworth-Pepin K., Delehaunty K.,
RA   Markovic C., Minx P., Feng Y., Kremitzki C., Mitreva M., Glasscock J.,
RA   Wylie T., Wohldmann P., Thiru P., Nhan M.N., Pohl C.S., Smith S.M.,
RA   Hou S., Nefedov M., de Jong P.J., Renfree M.B., Mardis E.R.,
RA   Wilson R.K.;
RT   "Genome analysis of the platypus reveals unique signatures of
RT   evolution.";
RL   Nature 453:175-183(2008).
RN   [2] {ECO:0000313|Ensembl:ENSOANP00000016505}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000016505};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00788929}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOANP00000016505}.
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DR   STRING; 9258.ENSOANP00000016505; -.
DR   Ensembl; ENSOANT00000016508; ENSOANP00000016505; ENSOANG00000010408.
DR   eggNOG; KOG3676; Eukaryota.
DR   eggNOG; ENOG4110DG4; LUCA.
DR   GeneTree; ENSGT00550000074425; -.
DR   InParanoid; F6U8Z0; -.
DR   OMA; HANCTAP; -.
DR   OrthoDB; EOG091G016O; -.
DR   TreeFam; TF314711; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000010408; -.
DR   GO; GO:0005929; C:cilium; IBA:GO_Central.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005262; F:calcium channel activity; IBA:GO_Central.
DR   GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR   GO; GO:0006874; P:cellular calcium ion homeostasis; IBA:GO_Central.
DR   GO; GO:0071476; P:cellular hypotonic response; IBA:GO_Central.
DR   GO; GO:0007231; P:osmosensory signaling pathway; IBA:GO_Central.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR024862; TRPV.
DR   InterPro; IPR008347; TRPV1-4_channel.
DR   InterPro; IPR008348; TRPV4_channel.
DR   PANTHER; PTHR10582; PTHR10582; 1.
DR   PANTHER; PTHR10582:SF39; PTHR10582:SF39; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01768; TRPVRECEPTOR.
DR   SMART; SM00248; ANK; 2.
DR   SUPFAM; SSF48403; SSF48403; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00844120};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   Ion channel {ECO:0000256|SAAS:SAAS00816195};
KW   Ion transport {ECO:0000256|SAAS:SAAS00816776};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00816535}.
FT   TRANSMEM    328    347       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    353    372       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    393    415       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    472    496       Helical. {ECO:0000256|SAM:Phobius}.
FT   REPEAT      108    140       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   DOMAIN      108    140       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
SQ   SEQUENCE   515 AA;  57357 MW;  2DCE0E5DFDDDFF6D CRC64;
     KETPSVKAPA PHPPPILKVF NRPILFDIVS RGSTADLDGL LSFLLTHKKR LTDEEFREPS
     TGKTCLPKAL LNLCNGRNDT IPLLLDIAER TGNTREFINS PFRDVYYRGQ TALHIAIERR
     CKHYVELLVA LGADVHAQAR GRFFQPKDEG GYFYFGKAGG GGARGLAGGQ GRGETEGWHG
     TRGDRGGXKF VTKMYDLLLV QCKKQFPDRH LETVLNNDGL SPLMMAAKTG KIGVFQHIIR
     REVKDEEVRH LSRKFKDWAY GPVYSSLYDL SSLDTCGEEA SVLEILVYNS KIEVSARATR
     STRRWSWPGS RGTRGASPTD GVGSKPRIAS NCSFIYSVLV MVSALYLGGV EAYEAVMVFA
     LVLGWMNALY FTRGLKLTGT YSIMIQKILF KDLFRFLLVY LLFMIGYASA LVSLLNPCPG
     REACPRGQSN CTVPTYPSCR DSETFSVFLL DLFKLTIGMG DLEMLGSTKY PVVFVILLVT
     YIILTFVLLL NMLIALMGET VGQVSKQSKH IWKLQ
//
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