ID F6UEX7_XENTR Unreviewed; 372 AA.
AC F6UEX7;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000041897};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000041897}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000041897};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000041897}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. CEA family.
CC {ECO:0000256|ARBA:ARBA00038222}.
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DR AlphaFoldDB; F6UEX7; -.
DR Ensembl; ENSXETT00000041897; ENSXETP00000041897; ENSXETG00000019334.
DR eggNOG; ENOG502S42Z; Eukaryota.
DR HOGENOM; CLU_024555_1_0_1; -.
DR InParanoid; F6UEX7; -.
DR TreeFam; TF336859; -.
DR Reactome; R-XTR-1566977; Fibronectin matrix formation.
DR Reactome; R-XTR-163125; Post-translational modification: synthesis of GPI-anchored proteins.
DR Reactome; R-XTR-202733; Cell surface interactions at the vascular wall.
DR Reactome; R-XTR-6798695; Neutrophil degranulation.
DR Bgee; ENSXETG00000019334; Expressed in testis.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44427:SF10; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 16; 1.
DR PANTHER; PTHR44427; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 291..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 113..198
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 203..272
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 372 AA; 40661 MW; 010FC2B562B8C74F CRC64;
MDGAHGSGVQ LIPQYPVVNQ SVTLSVTGVN GTIEKFTWYK VLNAHDYNQI LSVIPSLNTV
TKGPQYFSRA SQFPNGSLQI SGLVPADQGT YTVQIQTAEN ITWFPVLLPV YEPVTKPVMR
SSSSQSLVNE TVTLTCVTMH AERILWRKDG NGLPSGIDLS SDNRTATFHR INRWDAGQYQ
CEAENPISRN ISDSITLTVI YGPENVKSLL HVNTGSVPSL QCVADSVPAP SYLWRINGTI
ISNNTISVLQ DKSQDQLAYI CEVYNSVTRR VAIISVHVAI IGGQSYCVTS MAGIICGSIA
GTGLIICTMV LLYKRYVLPL RNSQKGQSSG RQDSSKIYNN AGNSAMNVSV REESAYMGLL
ELPQNVYTEL QQ
//
