ID F6UST4_CALJA Unreviewed; 1696 AA.
AC F6UST4;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Myosin VC {ECO:0000313|Ensembl:ENSCJAP00000001605.4};
GN Name=MYO5C {ECO:0000313|Ensembl:ENSCJAP00000001605.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000001605.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000001605.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000001605.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR STRING; 9483.ENSCJAP00000001605; -.
DR Ensembl; ENSCJAT00000001706.5; ENSCJAP00000001605.4; ENSCJAG00000000926.6.
DR GeneTree; ENSGT00940000157971; -.
DR HOGENOM; CLU_000192_7_2_1; -.
DR InParanoid; F6UST4; -.
DR Proteomes; UP000008225; Chromosome 10.
DR Bgee; ENSCJAG00000000926; Expressed in testis and 6 other cell types or tissues.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 6.10.220.10; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 4.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 5.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 4.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 8..62
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 67..753
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1421..1696
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 632..654
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 884..1091
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1211..1351
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 161..168
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1696 AA; 197611 MW; BE1B4683ADF24AB5 CRC64;
MAVAELYTQY NRVWIPDPEE VWKSAEIAKD YRVGDKILRL LLEDGTELDY SVDPESLPPL
RNPDILVGEN DLTALSYLHE PAVLHNLRIR FAESKLIYTY SGIILVAMNP YKQLPIYGDA
IIHAYSGQNM GDMDPHIFAV AEEAYKQMAR NNRNQSIIVS GESGAGKTVS ARYAMRYFAT
VSKSGSNTHV EDKVLASNPI TEAVGNAKTT RNDNSSRFGK YTEISFDERN QIIGANMRTY
LLEKSRVVFQ SENERNYHIF YQLCASAQQS EFKHLKLGSA EEFNYTRMGG NTVIEGVNDQ
AEMVETQKTF TLLGFKEDFQ MDVFKILAAI LHLGNVQIAA VGSERSSISE DDHHLEVFCE
LLGLESGRVA QWLCNRRIVT SSETVVKPMT RPQAVNARDA LAKKIYAHLF DFIVESINQA
LQFSGKQHTF IGVLDIYGFE TFDVNSFEQF CINYANEKLQ QQFNMHVFKL EQEEYMKENI
PWTLIDFYDN QPVIDLIEAK MGILELLDEE CLLPHGTDEN WLQKLYNNFV NKNPLFEKPR
MSNTSFVIQH FADKVEYKCE GFLEKNRDTV YDMLVEILRA SKFHLCASFF QENQVPPSPF
SSMITVKSAK QVIKPNSKHF RTTVGSKFRS SLYLLMETLN ATTPHYVRCI KPNDEKLPFE
FDSKRIVQQL RACGVLETIR ISAQSYPSRW TYIEFYSRYS ILMTKQELSF SDKKEVCKAV
LHRFIQDSNQ YQFGKTKIFF RAGQVAYLEK LRLDKLRQSC VMIQKHIRGW LQRKKFLRER
RAALIIQQYF RGQQTVRKAI TAMALKEAWA AIIIQKHCRG YLVCSLYRLI RVATITIQAY
TRGFLARRRY RKMLEEHKAV ILQKYARAWL ARRRFQSIRR FVLNIQLTYR VQRLQKKLED
QNKENHGLVE KLTSLAALRA GDVEKIQKLE TELERAATHR QHYEERGKRY RGTVEEKLAK
LQKHNSELET EKEKIQLKLQ EKTEELKEKM DNLTKQLFDD VQKEERQRML LEKSFELKTQ
DYEKQIQSLK EEIKALNDEK MQLQHLVEEG RITSDGLKAE VARLSSQAKT ISEFEKEIEL
LQAQKIDVEK HVQLQKREMR EKMSEITKQL LESYDIEDVR SRLSVEDLEH LNEDGELWFA
YEGLKKATRV LESHFQSQKD CYEKEIEALN FKVVHLSQEI NHLQKLFREE NDINESIRHE
VTRLTSENMM IPDFKQQISE LEKQKQDLEI RLNEQAEKMK GKLEELSNQL NRSQEEEGTQ
RKAIEAQNEI HTKEKEKLID KIQAMQEASE HLKKQFETES EVKSNFRQEA SRLTLENRDL
EEELDMKDRV IKKLQDQVKM LSKTVGKAND VYSSSGPKEY LGMLQYKRED EVKLIQNLIL
DLKPRGVVVN MIPGLPAHIL FMCVRYADSL NDANMLKSLM NSTINGIKQV VKEHLEDFEM
LSFWLSNTCH FLNCLKQYSG EEEFMKHNSP QQNKNCLNNF DLSEYRQILS DVAIRIYHQF
IIVMENNIQP IIVPGMLEYE SLQGISGLKP TGFRKRSSSI DDTDAYTMTS VLQQLSYFYS
TMCQNGLDPE LVRQAVKQLF FLIGAVTLNS LFLRKDMCSC RKGMQIRCNI SYLEEWLKDK
NLQNSLAKET LEPLSQAAWL LQVKKTTDSD AKEIYERCTS LSTVQIIKIL NSYTPIDDFE
KRVTPSFVRK VQLHLG
//
