ID F6UXB8_XENTR Unreviewed; 309 AA.
AC F6UXB8;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 3.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSXETP00000045067, ECO:0000313|RefSeq:XP_002934951.1, ECO:0000313|RefSeq:XP_004916873.1};
GN Name=LOC100495907 {ECO:0000313|Ensembl:ENSXETP00000045067,
GN ECO:0000313|RefSeq:XP_002934951.1, ECO:0000313|RefSeq:XP_004916873.1,
GN ECO:0000313|RefSeq:XP_012824588.1, ECO:0000313|RefSeq:XP_012824589.1,
GN ECO:0000313|Xenbase:XB-GENE-29082879};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000045067};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000045067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000045067};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000045067}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_002934951.1, ECO:0000313|RefSeq:XP_004916873.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_002934951.1,
RC ECO:0000313|RefSeq:XP_004916873.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_002934951.1,
RC ECO:0000313|RefSeq:XP_004916873.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR RefSeq; XP_002934951.1; XM_002934905.5.
DR RefSeq; XP_004916873.1; XM_004916816.4.
DR RefSeq; XP_012824588.1; XM_012969134.3.
DR RefSeq; XP_012824589.1; XM_012969135.3.
DR Ensembl; ENSXETT00000045067; ENSXETP00000045067; ENSXETG00000020872.
DR GeneID; 100495907; -.
DR KEGG; xtr:100495907; -.
DR Xenbase; XB-GENE-29082879; LOC100495907.
DR eggNOG; KOG0763; Eukaryota.
DR HOGENOM; CLU_015166_16_3_1; -.
DR OMA; GTAAWFM; -.
DR OrthoDB; 4064096at2759; -.
DR TreeFam; TF314880; -.
DR Proteomes; UP000008143; Chromosome 8.
DR Bgee; ENSXETG00000020872; Expressed in blastula and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 2.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45624; MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR45624:SF11; MITOCHONDRIAL ORNITHINE TRANSPORTER 1-LIKE; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|RuleBase:RU000488}.
FT TRANSMEM 14..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 12..96
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 109..203
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 214..300
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 309 AA; 33528 MW; D20B991FFB033A1D CRC64;
MPSEKAPPTH LKQILINLIA GAMGGVACVV SGQPFDTAKV KMQTFPTMYR GFVDCAVRTY
HAEGLRGLYH GTTPALVANA AENAVLFACY GFCQNLVSRC LGLQDPSQLS DWHKATAGSL
ASVFSSLALC PTELVKCRIQ TQHEMRLSGN KDIPHKSTPW SVVRAILSSE GIPGLFRGLS
STWLREIPGY FFFFGGYELS IDILSQRESS KDPPGALVVT VSGGVGGACF WLAVYPVDSV
KSRVQVLTLT PHSKGFIISL LHILRTEGFL PLYSGLMPTV VRAFPSNAAL FLAYEMTKRT
LTEYCCAPI
//
