ID F6UZJ8_XENTR Unreviewed; 733 AA.
AC F6UZJ8;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=CD2-associated protein {ECO:0000313|Ensembl:ENSXETP00000024712};
GN Name=cd2ap {ECO:0000313|Ensembl:ENSXETP00000024712};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000024712};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000024712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000024712};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000024712}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
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DR AlphaFoldDB; F6UZJ8; -.
DR Ensembl; ENSXETT00000024712; ENSXETP00000024712; ENSXETG00000007774.
DR AGR; Xenbase:XB-GENE-987810; -.
DR Xenbase; XB-GENE-987810; cd2ap.
DR HOGENOM; CLU_024255_2_0_1; -.
DR Bgee; ENSXETG00000007774; Expressed in 4-cell stage embryo and 12 other cell types or tissues.
DR ExpressionAtlas; F6UZJ8; baseline.
DR CDD; cd12053; SH3_CD2AP_1; 1.
DR CDD; cd12054; SH3_CD2AP_2; 1.
DR CDD; cd12056; SH3_CD2AP_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR035775; CD2AP_SH3_1.
DR InterPro; IPR035777; CD2AP_SH3_3.
DR InterPro; IPR035776; CD2AP_SH_2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167:SF23; CD2-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
PE 4: Predicted;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 6..66
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 113..172
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 281..342
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 170..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 239..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 645..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..510
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..620
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 663..678
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 81104 MW; EB977292B4FD85F8 CRC64;
MLGSSWARME YIVEYDYDAV NEDELTIRVG DVIKNVNKLE EDGWLEGEVN GKRGAFPDNF
VKEVKKDPEP KEENVSNKRE KSGNVASLVQ RMSVYGIPGM GPPPQPKSIK KKSKKRQCKV
LYEYIPQNED ELELKVGEVL DIIEEVEEGW WSGSNSGKSG LFPSNFVKEI DLSDDGESQE
STEDSEPSVT TPIATPASPV LSPANGPDAS PLATAQPKKV MGVGFGDIFK EGSVKLKTRL
PAPEPEVKKP EKPLPVQPSG TKVLRSTSSD ASRTETDSKP KAKEICKALF NYESVNEDEL
SFKEGDIIHL TSKETGDPGW WKGELNGKEG VFPDNFVAII QDSEKEVSLR APKPELRIAE
KKSTPTKTEE KDEKPLVDLK PPKPAAPQVP PKKPNLTSKS NSILKPAVIP PKRPEKPAFA
SPTSKPNGDL LLNRAKPESE TFNKAKTEPD PQVPSRPKPA EAEPHNKTKT DLEQILSRPK
SEVEPHNKTK TDLEQILNRP KSEAEPLNKT KMDLEQILSR PKSNGEHHNK TKMDLEHILS
RPKSVEVEPA AKSPRDEVDF FGDVIPTSNH LSHPTASRPK MQGKRPPGRF NGSTAQSKDV
TDSVKVLKEE EEESAKVKTP EVKKPLVSSP GPFALSVSPL VPLPVSKPAP SPQVPLPAEV
KVKSDVTDSK KSEKSEMEEL KAQIGELLSI VDALRKEHRK EMDHLKKELE EERLLRTSLE
TEVDKLKKAV QLT
//
