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Database: UniProt
Entry: F6W757_ORNAN
LinkDB: F6W757_ORNAN
Original site: F6W757_ORNAN 
ID   F6W757_ORNAN            Unreviewed;       463 AA.
AC   F6W757;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 2.
DT   30-AUG-2017, entry version 28.
DE   SubName: Full=ALG11, alpha-1,2-mannosyltransferase {ECO:0000313|Ensembl:ENSOANP00000024454};
GN   Name=ALG11 {ECO:0000313|Ensembl:ENSOANP00000024454};
OS   Ornithorhynchus anatinus (Duckbill platypus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX   NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000024454, ECO:0000313|Proteomes:UP000002279};
RN   [1] {ECO:0000313|Ensembl:ENSOANP00000024454}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000024454};
RX   PubMed=8919867; DOI=10.1007/BF02198841;
RA   Janke A., Gemmell N.J., Feldmaier-Fuchs G., von Haeseler A., Paabo S.;
RT   "The mitochondrial genome of a monotreme--the platypus
RT   (Ornithorhynchus anatinus).";
RL   J. Mol. Evol. 42:153-159(1996).
RN   [2] {ECO:0000313|Proteomes:UP000002279}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Glennie {ECO:0000313|Proteomes:UP000002279};
RX   PubMed=18464734; DOI=10.1038/nature06936;
RA   Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E.,
RA   Ponting C.P., Grutzner F., Belov K., Miller W., Clarke L.,
RA   Chinwalla A.T., Yang S.P., Heger A., Locke D.P., Miethke P.,
RA   Waters P.D., Veyrunes F., Fulton L., Fulton B., Graves T., Wallis J.,
RA   Puente X.S., Lopez-Otin C., Ordonez G.R., Eichler E.E., Chen L.,
RA   Cheng Z., Deakin J.E., Alsop A., Thompson K., Kirby P.,
RA   Papenfuss A.T., Wakefield M.J., Olender T., Lancet D., Huttley G.A.,
RA   Smit A.F., Pask A., Temple-Smith P., Batzer M.A., Walker J.A.,
RA   Konkel M.K., Harris R.S., Whittington C.M., Wong E.S., Gemmell N.J.,
RA   Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J., Zemann A.,
RA   Churakov G., Kriegs J.O., Brosius J., Murchison E.P.,
RA   Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D.,
RA   Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A.,
RA   Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H.,
RA   Taylor J., Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y.,
RA   Huang X., Stark A., Kheradpour P., Kellis M., Flicek P., Chen Y.,
RA   Webber C., Hardison R., Nelson J., Hallsworth-Pepin K., Delehaunty K.,
RA   Markovic C., Minx P., Feng Y., Kremitzki C., Mitreva M., Glasscock J.,
RA   Wylie T., Wohldmann P., Thiru P., Nhan M.N., Pohl C.S., Smith S.M.,
RA   Hou S., Nefedov M., de Jong P.J., Renfree M.B., Mardis E.R.,
RA   Wilson R.K.;
RT   "Genome analysis of the platypus reveals unique signatures of
RT   evolution.";
RL   Nature 453:175-183(2008).
RN   [3] {ECO:0000313|Ensembl:ENSOANP00000024454}
RP   IDENTIFICATION.
RC   STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000024454};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSOANP00000024454}.
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DR   STRING; 9258.ENSOANP00000024454; -.
DR   Ensembl; ENSOANT00000024458; ENSOANP00000024454; ENSOANG00000015524.
DR   eggNOG; KOG1387; Eukaryota.
DR   eggNOG; COG0438; LUCA.
DR   GeneTree; ENSGT00550000075118; -.
DR   InParanoid; F6W757; -.
DR   OrthoDB; EOG091G0803; -.
DR   TreeFam; TF313056; -.
DR   Proteomes; UP000002279; Unplaced.
DR   Bgee; ENSOANG00000015524; -.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004377; F:GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0006490; P:oligosaccharide-lipid intermediate biosynthetic process; IBA:GO_Central.
DR   GO; GO:0033577; P:protein glycosylation in endoplasmic reticulum; IBA:GO_Central.
DR   InterPro; IPR031814; ALG11_N.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   Pfam; PF15924; ALG11_N; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002279};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     24     46       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    239    260       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       67    273       ALG11_N. {ECO:0000259|Pfam:PF15924}.
FT   DOMAIN      297    457       Glycos_transf_1. {ECO:0000259|Pfam:
FT                                PF00534}.
SQ   SEQUENCE   463 AA;  51377 MW;  312C7AD806679399 CRC64;
     KDGEGERIEV PNQQVTLERF LCSLLFPGLI VSGALCVCLV IVLLGIRLWL QKKKKAFAAG
     KNGKSQTVVA FFHPYCNAGG GGERVLWCAL RALQKKYPEA LYVVYTGDND VTGEQMVEGA
     LRRFNVRLAL PVKFVFLRKR YLVEASLYPH FTLLGQSLGS VFLGWEALAA CVPDVYVDSM
     GYAFTLPLFK YLGGCRVGCY VHYPTISTDM LTVVREQTAA FNNASFITKN PVLSKVKLLY
     YYTFALAYGL VGSCADVVMV NSSWTLSHIL ALWKAGPRTS VVYPPCDVRA FLDVPLHEKN
     LLVSVGQFRP EKNHPLQIRA FARLLGKEAA KMLPSLKLVL IGGCRNQEDE QRVSHLRELC
     RDLGVGESVE FKINIPFEEL KRYLAEATIG LHTMWNEHFG IGVVECMAAG TVILAHDSGG
     PKLDIVVPHE GNITGFLAES EESYAETIAH ILSLSPEERL QIR
//
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