ID F6WHA5_XENTR Unreviewed; 1507 AA.
AC F6WHA5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Leucine-rich repeat-containing protein 9 {ECO:0000313|Ensembl:ENSXETP00000036989, ECO:0000313|RefSeq:XP_031746458.1};
GN Name=lrrc9 {ECO:0000313|Ensembl:ENSXETP00000036989,
GN ECO:0000313|RefSeq:XP_031746458.1,
GN ECO:0000313|Xenbase:XB-GENE-1011352};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000036989};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000036989}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000036989};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000036989}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_031746458.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_031746458.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_031746458.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_031746458.1; XM_031890598.1.
DR Ensembl; ENSXETT00000036989; ENSXETP00000036989; ENSXETG00000016981.
DR AGR; Xenbase:XB-GENE-1011352; -.
DR Xenbase; XB-GENE-1011352; lrrc9.
DR Proteomes; UP000008143; Chromosome 8.
DR Bgee; ENSXETG00000016981; Expressed in testis and 4 other cell types or tissues.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 7.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF9; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF14580; LRR_9; 2.
DR SMART; SM00364; LRR_BAC; 8.
DR SMART; SM00365; LRR_SD22; 16.
DR SMART; SM00369; LRR_TYP; 13.
DR SUPFAM; SSF52075; Outer arm dynein light chain 1; 5.
DR PROSITE; PS51450; LRR; 16.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 318..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1479..1507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1507 AA; 172072 MW; B71E0990485BC697 CRC64;
MLSNENLNSE EIIRELCACN GLSFEKIRQD GPATTTLEMF FSGYPKMAGL SYFPNLTQLI
LVGQNIHCIA GLESCHFLKE LWITECHLSK IQGLHHCADL QKLYLYHNEI SVIEGLENLL
KLEVLWLNNN QINVIEGLDM MQNLKELNLA NNLIHSIGES LDPNVQLERL NLSGNKISSF
KELTNLARLP SLMDLGLKDP QYSPNPVCLL CNYAIHVLYH IPQLQRLDTY DVSEKQIKNL
AESTVVKKIM YYNMRMKNNQ RQQREELEKV RERTSKAKQV PENRIRALSF LVKNLEHELT
DMQSSGNMQA NIPISNKFHE NNCDTEESNS QQSSERRKNN SDRLEQIHKK ICALKERMIF
WTRKLSEVEK HHEEKCRRMK DSFHLLDQFL QTELETVGNV RFEEGTAADS WFKSCYDLIV
SRFCAMNFRA YGISGIKIHR IVRVHNRILR LKFEDKVQYW MDNEDLYTTE SYKKKLEYLF
YIFDPKLPID KKELLHVLEN GCNITRSSQL PEQEQVEAVL LTNSMSLCEG PRLEFLQKQA
MNKSCDPEAF KDGIIVIAKV FLGRSVKARD DLPIKPNNYA KVNSVYRLQK FANSTFNSLN
DEICSSKEHG NCDCSLRQCE WLVFDHEFIL PEYVVEFEYI SMEKSSGFVT PSNENAEDVS
HDLKLDEDAI ALEPFLKPKP KIISLDEKTV LSVARANIYS QITVLNLHGN SLSKLKDISR
LNGLRKLIIS FNEFSSLEDV SYLTNLEYLD ASHNQVITLE GFKGLGKLKY LDLSWNKLTN
SREDLHILRK HAIQLSSLDI RYNFWQKPAS VLKDTIAILP SLTHLNGVTI TEDEISEALQ
ISSGSRITQA SLLINARTDT VKPRCLNLLP SAQILAQFSK NCLDPNAELS NSWYTKITSL
TLDSQNLVRI TNLEKLVNLR WASFSSNHLT KIEGLEHCVN LEELNLDDNS ISKLEGLSKL
TKLRRLSINN NLLAGFDRHV IESLSHLHFL SAENNNISSL AGLQRGYKLI ELYLSNNCIS
SNQEIYSLKG LNNLVILDMW GNPILLKHEN YRLFVIFHLS AIKALDGVAV EPSECENAKD
MFGGRLTSDM IAERIGHQRF TELQDLNWRT SSIRSIDLVP ADHFRNVQTV NLENNNLTSF
SGLIFLPNIK NLYLNHNRIE SILPQQKSQS HLTNRQILHQ KVSSSGYGQQ GTSKGSRDTV
YGEALSPVMQ SLEVLHLGYN GINSLPMLQL GRLRNLKSLY LQGNEISHVE GLENLQFLRE
LVLDHNRIKA IAETSFAKLN SLVSLNLEEN RLRDLNNLPP LLKLRKLLIG SNKIQEISEI
EKLEVIPALV ELSISGNPIS RKPFLRNLLV VRLQNLQILD GILITAEDRA RAEMYFMEQQ
SLTVPNAVMD LGNPVSTMIV SKPLPLRVTN FPLAGGAHHS LGADLHFNNG HEDIFQNEAN
KYKKLKNYTV GVGHNPQNTQ DIALRQLRGG THFPASYLTQ QSGQARSQQK HPFNQENEGR
MQRNLSD
//
