ID F6WZZ6_MACMU Unreviewed; 916 AA.
AC F6WZZ6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Transcription termination factor 1 {ECO:0000313|Ensembl:ENSMMUP00000040058.3};
GN Name=TTF1 {ECO:0000313|Ensembl:ENSMMUP00000040058.3,
GN ECO:0000313|VGNC:VGNC:78669};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000040058.3, ECO:0000313|Proteomes:UP000006718};
RN [1] {ECO:0000313|Proteomes:UP000006718}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17573 {ECO:0000313|Proteomes:UP000006718};
RX PubMed=17431167; DOI=10.1126/science.1139247;
RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., Wilson R.K.,
RA Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., Hardison R.C.,
RA Makova K.D., Miller W., Milosavljevic A., Palermo R.E., Siepel A.,
RA Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., Dinh H.H.,
RA Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., Godfrey J.,
RA Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N.,
RA Joshi V., Khan Z.M., Kirkness E.F., Cree A., Fowler R.G., Lee S.,
RA Lewis L.R., Li Z., Liu Y.-S., Moore S.M., Muzny D., Nazareth L.V.,
RA Ngo D.N., Okwuonu G.O., Pai G., Parker D., Paul H.A., Pfannkoch C.,
RA Pohl C.S., Rogers Y.-H.C., Ruiz S.J., Sabo A., Santibanez J.,
RA Schneider B.W., Smith S.M., Sodergren E., Svatek A.F., Utterback T.R.,
RA Vattathil S., Warren W., White C.S., Chinwalla A.T., Feng Y., Halpern A.L.,
RA Hillier L.W., Huang X., Minx P., Nelson J.O., Pepin K.H., Qin X.,
RA Sutton G.G., Venter E., Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P.,
RA Jones S.M., Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L.,
RA Csuros M., Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H.,
RA Liu Y., Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., Denby A.,
RA Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., Marklein A.,
RA Nielsen R., Vallender E.J., Clark A.G., Ferguson B., Hernandez R.D.,
RA Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., Pu L.-L., Ren Y.,
RA Smith D.G., Wheeler D.A., Schenck I., Ball E.V., Chen R., Cooper D.N.,
RA Giardine B., Hsu F., Kent W.J., Lesk A., Nelson D.L., O'brien W.E.,
RA Pruefer K., Stenson P.D., Wallace J.C., Ke H., Liu X.-M., Wang P.,
RA Xiang A.P., Yang F., Barber G.P., Haussler D., Karolchik D., Kern A.D.,
RA Kuhn R.M., Smith K.E., Zwieg A.S.;
RT "Evolutionary and biomedical insights from the rhesus macaque genome.";
RL Science 316:222-234(2007).
RN [2] {ECO:0000313|Ensembl:ENSMMUP00000040058.3}
RP IDENTIFICATION.
RC STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000040058.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6WZZ6; -.
DR STRING; 9544.ENSMMUP00000040058; -.
DR PaxDb; 9544-ENSMMUP00000040058; -.
DR Ensembl; ENSMMUT00000047027.3; ENSMMUP00000040058.3; ENSMMUG00000006833.4.
DR VEuPathDB; HostDB:ENSMMUG00000006833; -.
DR VGNC; VGNC:78669; TTF1.
DR eggNOG; KOG0051; Eukaryota.
DR GeneTree; ENSGT00940000159729; -.
DR HOGENOM; CLU_016962_1_0_1; -.
DR InParanoid; F6WZZ6; -.
DR OMA; MQESRPA; -.
DR OrthoDB; 457673at2759; -.
DR TreeFam; TF333537; -.
DR Proteomes; UP000006718; Chromosome 15.
DR Bgee; ENSMMUG00000006833; Expressed in ileum and 23 other cell types or tissues.
DR GO; GO:0001650; C:fibrillar center; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003682; F:chromatin binding; IBA:GO_Central.
DR GO; GO:0006363; P:termination of RNA polymerase I transcription; IBA:GO_Central.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR001005; SANT/Myb.
DR PANTHER; PTHR46760; TRANSCRIPTION TERMINATION FACTOR 1; 1.
DR PANTHER; PTHR46760:SF1; TRANSCRIPTION TERMINATION FACTOR 1; 1.
DR Pfam; PF13921; Myb_DNA-bind_6; 1.
DR SMART; SM00717; SANT; 2.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006718}.
FT DOMAIN 665..749
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 41..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..201
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 377..392
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..477
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 916 AA; 104465 MW; C4C37D413ED4DB67 CRC64;
MEGESRRFEI HTPVSDKKKK KYSAHKERPQ KHSHEIFRDS SLVSEQSQIT RRKKRKKDFQ
HLISSPLKKS RIHDDAENAT ATLKKRKKRR YSALEVEEEA GVTVVLVDKE NISNTPKPFR
KDVDVICVDM SMEQKLPGEP KTDKFQVLAK SHAHKSEALH NKIREKKNKK HRRKAASWDA
VQESQRAMDA LPQSESHQEE SWLSIGPGGE MTELPASAHK NKCKKKKKKS SNQEYETLAM
PEGSQAGSEA EPDMQESRPT VGLDGEAPEL LGPTHKKKSK KKKKKKSSYQ DSEALAMPEG
SQVGSEVATE TQESRPAVGL RGETAELPAP AYKNKSKKKK KKSNHQEFEA MAMPESLESA
YPEGSQVGRE VGIVEGRKAL KGFKESNSTE KKSKKRKLKS VKRAIASGDG FPVSSKNSES
TLFDSVEGDG AVMEESVKPR PRRKKTRACS ASKHMQEVPR LEPANEERNL ETAEDSETRY
LYADSGDADD SDADLGSAVR QLQEFIPNIK DRATSTIKRM YRDDLERFKE FKAQGVAIKF
GKFSVKENKQ LEKNVEDFLA LTGIESADKL LYTDRYPEEK SAITNLKRRH SFRLHIGRNI
ARPWKLIYYR AKKMFDVNNY KGRYSEGDTE KLKMYHSLLG NDWKTIGEMV ARSSLSVALK
FSQISSQRNR GTWSKSETQK LIKAVEEVIL KKMSPQELKE VDSKLQENPE SCLSIVREKL
YKGISWVEVE AKVQTRNWMQ CKSKWTEILT KRMTNGRRIY CGVNALRAKV SLIERLYEIN
VEDTNEIDWE DLASAIGDVP PSYVQTKFSR LKAIYVPFWQ KKTFPEIIDY LYETTLPFLK
EKLEKMLQKK GTEIQTPAAP KQVFPFRDIF YYEDDSEGED IEKESEGQAP WLTPVIPALW
EADASGSSEI RSSRPA
//
