ID F6X2H0_MOUSE Unreviewed; 157 AA.
AC F6X2H0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
DE Flags: Fragment;
GN Name=Trim41 {ECO:0000313|Ensembl:ENSMUSP00000118789.2,
GN ECO:0000313|MGI:MGI:2384814};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000118789.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000118789.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118789.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000118789.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000118789.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR MaxQB; F6X2H0; -.
DR PeptideAtlas; F6X2H0; -.
DR ProteomicsDB; 354840; -.
DR Antibodypedia; 17930; 245 antibodies from 26 providers.
DR Ensembl; ENSMUST00000138019.2; ENSMUSP00000118789.2; ENSMUSG00000040365.15.
DR AGR; MGI:2384814; -.
DR MGI; MGI:2384814; Trim41.
DR VEuPathDB; HostDB:ENSMUSG00000040365; -.
DR GeneTree; ENSGT00940000154294; -.
DR HOGENOM; CLU_013137_6_5_1; -.
DR ChiTaRS; Trim41; mouse.
DR Proteomes; UP000000589; Chromosome 11.
DR Bgee; ENSMUSG00000040365; Expressed in retinal neural layer and 258 other cell types or tissues.
DR ExpressionAtlas; F6X2H0; baseline and differential.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19760; Bbox2_TRIM4-like; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR020457; Znf_B-box_chordata.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF659; E3 UBIQUITIN-PROTEIN LIGASE TRIM41; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR PRINTS; PR01406; BBOXZNFINGER.
DR SMART; SM00336; BBOX; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 1: Evidence at protein level;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Proteomics identification {ECO:0007829|EPD:F6X2H0,
KW ECO:0007829|MaxQB:F6X2H0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00024}.
FT DOMAIN 81..122
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000118789.2"
FT NON_TER 157
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000118789.2"
SQ SEQUENCE 157 AA; 17997 MW; ECF477D674B1C42F CRC64;
XADLRGEDED EEEEVLEEDE EEELDPITQL PPPPAPRRCF TCPQCRKSFP RRSFRPNLQL
ANMVQVIRQM HPTPGRGSRV NEQGICPRHQ EALKLFCEVD EEAICVVCRE SRSHKQHSVV
PLEEVVQEYK SQMKSELAAV ASEFGRLTRF LAEEQAG
//
