GenomeNet

Database: UniProt
Entry: F6XBV3_MONDO
LinkDB: F6XBV3_MONDO
Original site: F6XBV3_MONDO 
ID   F6XBV3_MONDO            Unreviewed;      4896 AA.
AC   F6XBV3;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 2.
DT   30-AUG-2017, entry version 44.
DE   SubName: Full=Ryanodine receptor 2 {ECO:0000313|Ensembl:ENSMODP00000034966};
GN   Name=RYR2 {ECO:0000313|Ensembl:ENSMODP00000034966};
OS   Monodelphis domestica (Gray short-tailed opossum).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX   NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000034966, ECO:0000313|Proteomes:UP000002280};
RN   [1] {ECO:0000313|Ensembl:ENSMODP00000034966, ECO:0000313|Proteomes:UP000002280}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17495919; DOI=10.1038/nature05805;
RA   Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L.,
RA   Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J.,
RA   Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A.,
RA   Benos P.V., Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L.,
RA   Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M.,
RA   Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E.,
RA   Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M.,
RA   Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E.,
RA   Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A.,
RA   Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J.,
RA   Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J.,
RA   Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S.,
RA   Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A.,
RA   Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C.,
RA   Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA   Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P.,
RA   Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C.,
RA   Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K.,
RA   Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D.,
RA   Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G.,
RA   Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E.,
RA   Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C.,
RA   Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E.,
RA   Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K.,
RA   Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A.,
RA   Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R.,
RA   Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA   McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA   Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A.,
RA   Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N.,
RA   Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S.,
RA   Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F.,
RA   Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P.,
RA   Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D.,
RA   Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
RA   Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
RA   Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
RA   Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
RA   Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
RA   Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA   Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT   "Genome of the marsupial Monodelphis domestica reveals innovation in
RT   non-coding sequences.";
RL   Nature 447:167-177(2007).
RN   [2] {ECO:0000313|Ensembl:ENSMODP00000034966}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSMODP00000034966}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   STRING; 13616.ENSMODP00000034966; -.
DR   Ensembl; ENSMODT00000036554; ENSMODP00000034966; ENSMODG00000007421.
DR   eggNOG; KOG2243; Eukaryota.
DR   eggNOG; ENOG410YCNW; LUCA.
DR   GeneTree; ENSGT00760000119152; -.
DR   InParanoid; F6XBV3; -.
DR   OMA; EHMPNDT; -.
DR   OrthoDB; EOG091G00T0; -.
DR   TreeFam; TF315244; -.
DR   Proteomes; UP000002280; Chromosome 2.
DR   Bgee; ENSMODG00000007421; -.
DR   GO; GO:0034704; C:calcium channel complex; IEA:Ensembl.
DR   GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0043234; C:protein complex; IEA:Ensembl.
DR   GO; GO:0033017; C:sarcoplasmic reticulum membrane; IEA:Ensembl.
DR   GO; GO:0005790; C:smooth endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0030018; C:Z disc; IEA:Ensembl.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0048763; F:calcium-induced calcium release activity; IEA:Ensembl.
DR   GO; GO:0005516; F:calmodulin binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0034236; F:protein kinase A catalytic subunit binding; IEA:Ensembl.
DR   GO; GO:0034237; F:protein kinase A regulatory subunit binding; IEA:Ensembl.
DR   GO; GO:0043621; F:protein self-association; IEA:Ensembl.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0043924; F:suramin binding; IEA:Ensembl.
DR   GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
DR   GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IEA:Ensembl.
DR   GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR   GO; GO:0003300; P:cardiac muscle hypertrophy; IEA:Ensembl.
DR   GO; GO:0071313; P:cellular response to caffeine; IEA:Ensembl.
DR   GO; GO:0071872; P:cellular response to epinephrine stimulus; IEA:Ensembl.
DR   GO; GO:0005513; P:detection of calcium ion; IEA:Ensembl.
DR   GO; GO:0003143; P:embryonic heart tube morphogenesis; IEA:Ensembl.
DR   GO; GO:0072599; P:establishment of protein localization to endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0003220; P:left ventricular cardiac muscle tissue morphogenesis; IEA:Ensembl.
DR   GO; GO:1901896; P:positive regulation of calcium-transporting ATPase activity; IEA:Ensembl.
DR   GO; GO:0010460; P:positive regulation of heart rate; IEA:Ensembl.
DR   GO; GO:0051284; P:positive regulation of sequestering of calcium ion; IEA:Ensembl.
DR   GO; GO:0098735; P:positive regulation of the force of heart contraction; IEA:Ensembl.
DR   GO; GO:0086029; P:Purkinje myocyte to ventricular cardiac muscle cell signaling; IEA:Ensembl.
DR   GO; GO:0098910; P:regulation of atrial cardiac muscle cell action potential; IEA:Ensembl.
DR   GO; GO:0098904; P:regulation of AV node cell action potential; IEA:Ensembl.
DR   GO; GO:0010881; P:regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; IEA:Ensembl.
DR   GO; GO:0098907; P:regulation of SA node cell action potential; IEA:Ensembl.
DR   GO; GO:0098911; P:regulation of ventricular cardiac muscle cell action potential; IEA:Ensembl.
DR   GO; GO:0051209; P:release of sequestered calcium ion into cytosol; IBA:GO_Central.
DR   GO; GO:0014808; P:release of sequestered calcium ion into cytosol by sarcoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   GO; GO:0014850; P:response to muscle activity; IEA:Ensembl.
DR   GO; GO:0035994; P:response to muscle stretch; IEA:Ensembl.
DR   GO; GO:0051775; P:response to redox state; IEA:Ensembl.
DR   GO; GO:0097050; P:type B pancreatic cell apoptotic process; IEA:Ensembl.
DR   GO; GO:0086005; P:ventricular cardiac muscle cell action potential; IEA:Ensembl.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF13833; EF-hand_8; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002280};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002280};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4208   4227       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4429   4449       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4503   4522       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4639   4660       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4697   4718       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4773   4796       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       30     85       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       92    137       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      145    200       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      206    263       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      271    328       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      519    729       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      945   1142       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1277   1482       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     3952   3987       EF-hand. {ECO:0000259|PROSITE:PS50222}.
SQ   SEQUENCE   4896 AA;  557325 MW;  C6DED5C49BE38D8A CRC64;
     MLANTMEKAE GQVDIEKWKF MMKTAQGGGH RTLLYGHAIL LRHSYSGMYL CCLSTSRSST
     DKLAFDVGLQ EDTTGEACWW TIHPASKQRS EGEKVRVGDD LILVSVSSER YLHLSYGSDI
     LHVDAAFQQT LWSVAPISSG SEAAQGYLIG GDVLRLLHGH MDECLTVPSG EHGEEQRRTV
     HYEGGAVSIH ARSLWRLETL RVAWSGSHIR WGQPFRLRHV TTGKYLSLLD DKSLLLMDKE
     KADVKSTAFS FRSSKEKLDI GIRKEIDGMG TSEIKYGDSV CYIQHVDTGL WLTYQSVDVK
     SVRMGSIQRK AIMHHEGHMD DGLNLSRSQH EESRTARVIR STVFLFNRFI RGLDALSKKV
     KSSTIDLPIE SVSLSLQDLI GYFHPPDEHL EHEDKQNRLR ALKNRQNLFQ EEGMINLVLE
     CIDRLHVYSS AAHFADVAGK EAGESWKSIL NSLYELLAAL IRGNRKNCAQ FSGSLDWLIS
     RLERLEASSG ILEVLHCVLV ESPEALNIIK EGHIKSIISL LDKHGRNHKV LDVLCSLCVC
     HGVAVRSNQH LICDNLLPGR DLLLQTRLVN HVSSMRPNIF LGISEGSAQY RKWYYELMVD
     HTEPFVTAEA THLRVGWAST EGYSPYPGGG EEWGGNGVGD DLFSYGFDGL HLWSGCIART
     VSSPNQHLLR TDDVISCCLD LSAPSISFRI NGQPVQGMFE NFNIDGLFFP VVSFSAGIKV
     RFLLGGRHGE FKFLPPPGYA PCFEAVLPKE KLKVEHSREY KQDRTYSRDL LGPTVSLSQA
     AFTPVPVDTS QIVLPPHLER IREKLAENIH ELWVMNKIEL GWQYGPVRDD NKRQHPCLVE
     FSKLPEQERN YNLQMSLETL KTLLALGCHV GISDEHAEEK VKKMKLPKNY QLSSGYKPAP
     MDLSFIKLTP SQEAMVDKLA ENAHNVWARD RIRQGWTYGI QQDVKNRRNP RLVPYALLDD
     RTKKSNKDSL REAVRTLLGY GYNLEAPDQD HATRTEVCSG TGEKFRIFRA EKTYAVKTGR
     WYFEFEAVTA GDMRVGWSRL GCQPDQELGS DEQAFAFDGF KAQRWHQGSE HYGRSWQAGD
     VVGCMVDMNE HTMMFTLNGE ILLDDSGSEL AFKDFEVVDG FIPVCSLGVA QVGRMNFGKD
     VSTLKYFTIC GLQEGYEPFA VNTNRDITMW LSKRLPQFLQ VPSNHEHIEV TRIDGTIDSS
     PCLKVTQKSF SSQNSSTDIM FYRLSMPIEC AEVFSKTAAG GLPGTSLFGP KNDLEDYDAD
     SDFEVLMKTA HGHLVPDRVE KEKEATKPEF NNHKDYAQEK PSRLKQRFML RRTKPDYSTS
     HSARLTEDVL ADDRDDYDYL MQTSTYYYSV RIFPGQEPAN VWVGWITSDF HQYDTVFDLD
     RVRTVTVTLG DEKGKVHESI KRSNCYMVCA GESMSPGQGR NNNGLEIGCV VDAASGLLTF
     TANGKELSTY YQVEPSTKLF PAVFAQATSP NVFQFELGRI KNVMPLSAGL FKSEHKNPIP
     QCPPRLHVQF LTHVLWSRMP NQFLKVDVSR ISERQGWLVQ CVDPLQFMSL HIPEENRSVD
     ILELTEQEEL LKFHYHTLRL YSAVCALGNN RVAHALCSHV DEPQLLYAIE NKYMPGLLRT
     GYYDLLIDIH LSSYATARLM MNNEFIVPMT DETKSITLFP DENKKHGLPG IGLSTSLRPR
     MQFSSPSFVS ISNEYYQFSP EFPLDILKSK TIQMLTEAVK EGSLHARDPV GGTTEFLFVP
     LIKLFYTLLI MGIFNNEDLK HILQLIEPSV FKEAANKEEE NEVLEKELNT EDQGLEGGRE
     EEIRGEKMPK EGLLQMKLPE PVKLQMCLLL QYLCDCQVRH RIEAIVAFSD DFVAKLQDNQ
     RFRYNEVMQA LNMSAALTAR KTKEFRSPPQ EQINMLLNFK DDKSECPCPE DIRDQLLDFH
     EDLMTHCGIE LDEDGALDGN SDLTIRGRLL YLVEKVTYLK KKQTEKPIEN DSKKPSTLQQ
     LISETMVRWA QESVIEDPEL VRAMFVLLHR QYDGIGGLVR ALPKTYTING VSVEDTISLL
     ASLGQIRSLL SVRMGKEEEK LMIRGLGDIM NNKVFYQHPN LMRALGMHET VMEVMVNVLG
     GGESKEITFP KMVANCCRFL CYFCRISRQN QKAMFDHLSY LLENSSVGLA SPAMRGSTPL
     DVAAASVMDN NELALALREP DLEKVVRYLA GCGLQSCQML VTKGYPDIGW NPVEGERYLD
     FLRFAVFCNG ESVEENANVV VRLLIRRPEC FGPALRGEGG NGLLAAMEEA IKIAEDPTRD
     GPSPTNGSSK TLDLAAEEDD TIHMGNAIMT FYAALIDLLG RCAPEMHLIH AGKGEAIRIR
     SILRSLIPLG DLVGVISIAF QMPTIAKDGN VVEPDMSAGF CPDHKAAMVL FLDRVYGIEV
     QDFLLHLLEV GFLPDLRAAA SLDTAALSAT DMALALNRYL CTAVLPLLTR CAPLFAGTEH
     HASLIDSLLH TVYRLSKGCS LTKAQRDSIE VCLLSICGQL RPSMMQHLLR RLVFDVPLLN
     EHAKMPLKLL TNHYERCWKY YCLPGGWGNF GAASEEELHL SRKLFWGIFD ALSQKKYEQE
     LFKLALPCLS AVAGALPPDY MESNYVSMME KQSSMDSEGN FNPQPVDTSN ITIPEKLEYF
     INKYAEHTHD KWSMEKLANG WIYGEIYSDS SKVQPLMKPY KLLSEKEKEI YRWPIKESLK
     TMLAWGWRIE RTREGDSMAL YTRTRRISQT SQVSIDTAHG YSPRAIDMSN VTLSRDLHAM
     AEMMAENYHN IWAKKKKLEL EAKVGGGNHP LLVPYDTLTA KEKAKDREKA QDILKFLQIN
     GYAVSRGFKD LELDTPSIEK RFAYSFLQQL IRYVDEAHQY ILEFDGGSRS KGEHFPYEQE
     IKFFAKVVLP LIDQYFKNHR LYFLSAASRP LSTGGHASNK EKEMVTSLFC KLGVLVRHRI
     SLFGNDASSI VNCLHILGQT LDARTVMKTG MESVKIALRA FLDNAAEDLE KTMENLKQGQ
     FTHTRNQPKG VTQIINYTTV ALLPMLSSLF EHIGQHQFGE DLILEDVQVS CYRILTSLYA
     LGTSKSIYVE RQRSALGECL AAFAGAFPVA FLETHLNKHN TYSIYNTKST RERTALNLPT
     SVEEVCPNIP SLEKLMDEIV ELAESGIRYT QMPHVMEVIL PMLCSYMSRW WEHGPENNPE
     KADTCCTALN SEHMNTLLGN ILKIIYNNLG IDEGAWMKRL AVFSQPIINK VKSQLLKSHF
     LPLMEKLKNK AAVVVSDEDH LKAEARGDMS EAELLILDEF TTLARDLYAF YPLLIRFVDF
     NRAKWLKEPN SEAEELFRMV AEVFIFWSKS HNFKREEQNF VVQNEINNMS FLITDTKSKM
     SKAAVTDQER KKMKRKGDRY SMQTSLIVAA LKRLLPIGLN ICAPGDQELI ALAKNRFSMK
     DTEDEVRDII RSNLHLQGKL EDPAIRWQMA LYKDLPNRTE ETSDPEKTIE RVLDIANVLF
     HLEQKPTNMG RRYYSMVEHP QRSKKAVWHK LLSKQRKRAV VACFRMAPLY NLPRHRAVNL
     FLQGYEKSWI ETEEHYFEDK LIEDLAKPGL ELPEEDEGTK KVDPLHQLIL LFSRTALTEK
     CKLEEDFLYM AYADIMAKSC HDEEDDDGEE EVKSFEVTGS QRSKEKEMEK QKLLYQQARL
     HDRGAAEMVL QTISASKGDT GPMVAATLKL GIAILNGGNS TVQQKMLDYL KEKKDVGFFQ
     SLAGLMQSCS VLDLNAFERQ NKAEGLGMVT EEGSGEKVLQ DDEFTCDLFR FLQLLCEGHN
     SDFQNYLRTQ TGNNTTVNII ISTVDYLLRV QESISDFYWY YSGKDVIDEQ GQRNFSKAIQ
     VAKQVFNTLT EYIQGPCTGN QQSLAHSRLW DAVVGFLHVF AHMQMKLSQD SSQIELLKEL
     MDLQKDMVVM LLSMLEGNVV NGTIGKQMVD MLVESSNNVE MILKFFDMFL KLKDLTSSDT
     FKEYDPDGKG IISKRDFHKA MESHKHYTQS ETEFLLSCAE TDENETLDYE EFVKRFHEPA
     KDIGFNVAVL LTNLSEHMPN DTRLQTFLEL AESVLNYFQP FLGRIEIMGS AKRIERVYFE
     ISESSRTQWE KPQVKESKRQ FIFDVVNEGG EKEKMELFVN FCEDTIFEMQ LAAQISESDL
     NERSVNKEET EKEKPEEQEP RMGFFSIMTV KSALLALRYN ILTIMRMLSL KSLKKQMKRI
     KKMTMKDLVM ALFSSYWSIL VGLLHFISSV FRGFFRIMCS LLLGGSLVEG AKKIKVAELL
     ANMPDPTQDE VRGDGEEGER KALETALPTE DLTDLKELTE ESDLLSDIFG LDLKREGGQY
     KLIPHNPNAG LSDLMSNPIP VPEVQEKCQE QKVKEDEKEE KEETKSEPEK AEGEDGEKEE
     KAKEDKGKQK LRQLHTHRYG EPEVPESAFW KKIIAYQQKL LNYFARNFYN MRMLALFVAF
     AINFILLFYK VSTSSVVEGK EIPSPSASEN SRISSLDSTA HRLITVHYVL EESSGYMEPT
     LRILAILHTV ISFFCIIGYY CLKVPLVIFK REKEVARKLE FDGLYITEQP SEDDIKGQWD
     RLVINTQSFP NNYWDKFVKR KVMDKYGEFY GRDRISELLG MDKAALDFSD AREKKKPKKD
     SSLSAVLNSI DVKYQMWKLG VVFTDNSFLY LAWYMTMSVL GHYNNFFFAA HLLDIAMGFK
     TLRTILSSVT HNGKQLVLTV GLLAVVVYLY TVVAFNFFRK FYNKSEDGDT PDMKCDDMLT
     CYMFHMYVGV RAGGGIGDEI EDPAGDEYEI YRIIFDITFF FFVIVILLAI IQGLIIDAFG
     ELRDQQEQVK EDMETKCFIC GIGNDYFDTV PHGFETHTLQ EHNLANYLFF LMYLINKDET
     EHTGQESYVW KMYQERCWEF FPAGDCFRKQ YEDQLN
//
DBGET integrated database retrieval system