ID F6XK88_ORNAN Unreviewed; 686 AA.
AC F6XK88;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOANP00000001554.3};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000001554.3, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000001554.3}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000001554.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6XK88; -.
DR STRING; 9258.ENSOANP00000001554; -.
DR Ensembl; ENSOANT00000001555.3; ENSOANP00000001554.3; ENSOANG00000000982.5.
DR eggNOG; KOG1027; Eukaryota.
DR eggNOG; KOG4177; Eukaryota.
DR GeneTree; ENSGT00940000161114; -.
DR HOGENOM; CLU_022542_0_0_1; -.
DR InParanoid; F6XK88; -.
DR OMA; YGSESHK; -.
DR TreeFam; TF344032; -.
DR Proteomes; UP000002279; Unplaced.
DR Bgee; ENSOANG00000000982; Expressed in endometrium and 8 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0004540; F:RNA nuclease activity; IBA:GO_Central.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IBA:GO_Central.
DR CDD; cd10423; RNase_RNase-L; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.20.1440.180; KEN domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR010513; KEN_dom.
DR InterPro; IPR038357; KEN_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR042745; RNase-L_RNase.
DR PANTHER; PTHR24141; 2-5A-DEPENDENT RIBONUCLEASE; 1.
DR PANTHER; PTHR24141:SF1; 2-5A-DEPENDENT RIBONUCLEASE; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF06479; Ribonuc_2-5A; 1.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00580; PUG; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS51392; KEN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002279}.
FT REPEAT 55..87
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 199..232
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 326..546
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 549..680
FT /note="KEN"
FT /evidence="ECO:0000259|PROSITE:PS51392"
SQ SEQUENCE 686 AA; 77803 MW; 4AC9969B05F3A893 CRC64;
MKFFHLSSPD GTLEQKGTAS QEVNQKLVEA IKTGNIKEVR ELLERGADVH FQVEGGWMPL
HLAAQAEKED IVHLLLEKGA EPCARKKNGA TPFIVAAIKG NVKCETAAEG GLGILIRTRG
RCELKTEDQS NGPHGCSREG HLHIVQTLLD QMGADVNVRD NMGRNSLIRT FRKSTTENAE
SVAGCLLDHH INVNVRDESG KTPLILAVEQ KHLSLVQKLL EQNGTDVNDT DKEGKTALLV
AVEKQFKDIV CLLCEKGAKT DCGNLISIAN RQYNTDLADL LRRYGARENF HCSNTDWSPQ
SKQWGEQLKH LNRIYRPMIG KLKIFIEKEY KIAETSEGGV YLGFFDGQET AVKIFCDDSE
RAKKETDCIL EWRKNRHLVK HFGTEINNNS KYVCLSLCER NLEEHLKSHR DAGAEFTKDI
LKSLFKAVQE LHQFGFVHQD LHPKNILIDS KDEVCLADFD KSCRFANDQT LVHGDFQALG
RLVQYVVTKG EDPFVEKGAA GEPQEVGAGL SEIPDHAETV DLIQILLSPG VARQTQLSDI
LYHPFFWPCN MRYRFLRDVG NESDIKTRNT ENMTLKKLNH NPSESYSKWT SKIDKYVMTK
MNKFYKNEKY QYQDKVTDLL KLIRNIGEHI EEEANAGMKA LIGDSAQYFQ KTFPELVMHV
YKNIQNTEFM KHIPNAHNCL LNPPLR
//
