ID F6XNB6_MOUSE Unreviewed; 495 AA.
AC F6XNB6;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Kinesin family member 1B {ECO:0000313|Ensembl:ENSMUSP00000120076.2};
DE Flags: Fragment;
GN Name=Kif1b {ECO:0000313|Ensembl:ENSMUSP00000120076.2,
GN ECO:0000313|MGI:MGI:108426};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000120076.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0007829|PubMed:17242355}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=17242355; DOI=10.1073/pnas.0609836104;
RA Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
RT "Large-scale phosphorylation analysis of mouse liver.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
RN [2] {ECO:0007829|PubMed:18630941}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18630941; DOI=10.1021/pr800223m;
RA Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.;
RT "Specific phosphopeptide enrichment with immobilized titanium ion affinity
RT chromatography adsorbent for phosphoproteome analysis.";
RL J. Proteome Res. 7:3957-3967(2008).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000120076.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120076.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [5] {ECO:0000313|Ensembl:ENSMUSP00000120076.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000120076.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR jPOST; F6XNB6; -.
DR MaxQB; F6XNB6; -.
DR PeptideAtlas; F6XNB6; -.
DR ProteomicsDB; 306608; -.
DR Antibodypedia; 4196; 140 antibodies from 24 providers.
DR Ensembl; ENSMUST00000139123.8; ENSMUSP00000120076.2; ENSMUSG00000063077.16.
DR UCSC; uc012dpq.2; mouse.
DR AGR; MGI:108426; -.
DR MGI; MGI:108426; Kif1b.
DR VEuPathDB; HostDB:ENSMUSG00000063077; -.
DR GeneTree; ENSGT00940000157445; -.
DR HOGENOM; CLU_552720_0_0_1; -.
DR ChiTaRS; Kif1b; mouse.
DR Proteomes; UP000000589; Chromosome 4.
DR Bgee; ENSMUSG00000063077; Expressed in pigmented layer of retina and 274 other cell types or tissues.
DR ExpressionAtlas; F6XNB6; baseline and differential.
DR CDD; cd01233; PH_KIFIA_KIFIB; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR049780; PH_KIFIA_KIFIB.
DR PANTHER; PTHR47117:SF2; KINESIN-LIKE PROTEIN KIF1A ISOFORM X1; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:F6XNB6,
KW ECO:0007829|MaxQB:F6XNB6};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 380..478
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 299..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000120076.2"
SQ SEQUENCE 495 AA; 55302 MW; FD0E61F28483B815 CRC64;
XAVLSLNIIS AKSLKAAHSS SRLLLDKDIP RTFYRFEAVW DSSLHNSLLL NRVTPYGEKI
YMTLSAYLEL DHCIQPAVIT KDVCMVFYSR DAKISPPRSL RNLFGSGYSK SPDSNRVTGI
YELSLCKMAD TGSPGMQRRR RKVLDTSVAY VRGEENLAGW RPRGDSLILE HQWELEKLEL
LHEVEKTRHF LLLRERLGDS VPKSLSDSLS PSLSSGTLST STSISSQIST TTFESAITPS
ESSGYDSADV ESLVDREKEL ATKCLQLLTH TFNREFSQVH GSISDCKLSD ISPIGRDPSV
SSFSSSTLTP SSTCPSLVDS RSSSMDQKTP EANSRASSPC QEFEQFQIVP TVETPYLARA
GKNEFLNLVP DIEEVRAGSV VSKKGYLHFK EPLSSNWAKH FVVVRRPYVF IYNSDKDPVE
RGIINLSTAQ VEYSEDQQAM VKTPNTFAVC TKHRGVLLQA LNDKDMNDWL YAFNPLLAGT
IRSKLSRRCP SQPKY
//
