ID F6XQ90_ORNAN Unreviewed; 359 AA.
AC F6XQ90;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Solute carrier family 25 member 27 {ECO:0000313|Ensembl:ENSOANP00000013150.3};
GN Name=SLC25A27 {ECO:0000313|Ensembl:ENSOANP00000013150.3};
OS Ornithorhynchus anatinus (Duckbill platypus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Monotremata; Ornithorhynchidae; Ornithorhynchus.
OX NCBI_TaxID=9258 {ECO:0000313|Ensembl:ENSOANP00000013150.3, ECO:0000313|Proteomes:UP000002279};
RN [1] {ECO:0000313|Ensembl:ENSOANP00000013150.3}
RP IDENTIFICATION.
RC STRAIN=Glennie {ECO:0000313|Ensembl:ENSOANP00000013150.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; F6XQ90; -.
DR Ensembl; ENSOANT00000013152.3; ENSOANP00000013150.3; ENSOANG00000008273.3.
DR GeneTree; ENSGT00940000160098; -.
DR HOGENOM; CLU_015166_14_2_1; -.
DR InParanoid; F6XQ90; -.
DR OMA; FPFWKAV; -.
DR Proteomes; UP000002279; Unplaced.
DR Bgee; ENSOANG00000008273; Expressed in liver and 7 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:Ensembl.
DR GO; GO:0015108; F:chloride transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0015078; F:proton transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl.
DR GO; GO:0009409; P:response to cold; IBA:GO_Central.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45618; MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED; 1.
DR PANTHER; PTHR45618:SF8; MITOCHONDRIAL UNCOUPLING PROTEIN 4; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00784; MTUNCOUPLING.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Reference proteome {ECO:0000313|Proteomes:UP000002279};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT REPEAT 21..115
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 125..217
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 226..317
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 359 AA; 40138 MW; BEA4A5E3E7AE5160 CRC64;
MSPSKDEERR RSLAERWPGG SRFLLSCCAA VVAELATFPL DLTKTRLQIQ GEAALARYGE
PSGGSVPYRG MLRTAKGIVQ EEGVLKLWQG VTPAIYRHLV YSGGRMVTYE YLRESVLGKS
EDKHFPLWKA VMGGMIAGVI GQFFANPADL VKVQMQMEGK RKLEGKPSRF RGVHHAFAKI
LKEGGLRGLW AGWVPNVQRA ALVNMGDLTT YDSVKHFLLR NTSLQDNILT HSLSSLCSGL
VAATLGTPAD VIKSRIMNQP TDKQGRGLLY KSSIDCLIQT IKGEGFMSLY KGFVPSWMRM
KKRKALKLIK IQAMPRPKRT MLSTGVSEIP WPWLTTQNNL SEIKNLRERG EWLINKMTT
//
