ID F6XXP5_MOUSE Unreviewed; 234 AA.
AC F6XXP5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 27-JUL-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=GTP-binding protein 8 (putative) {ECO:0000313|Ensembl:ENSMUSP00000123974.2};
DE Flags: Fragment;
GN Name=Gtpbp8 {ECO:0000313|Ensembl:ENSMUSP00000123974.2,
GN ECO:0000313|MGI:MGI:1913317};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000123974.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000123974.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123974.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000123974.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000123974.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F6XXP5; -.
DR SMR; F6XXP5; -.
DR MaxQB; F6XXP5; -.
DR PeptideAtlas; F6XXP5; -.
DR ProteomicsDB; 357581; -.
DR Antibodypedia; 52345; 78 antibodies from 16 providers.
DR Ensembl; ENSMUST00000161436.2; ENSMUSP00000123974.2; ENSMUSG00000022668.11.
DR AGR; MGI:1913317; -.
DR MGI; MGI:1913317; Gtpbp8.
DR VEuPathDB; HostDB:ENSMUSG00000022668; -.
DR GeneTree; ENSGT00390000001083; -.
DR ChiTaRS; Gtpbp8; mouse.
DR Proteomes; UP000000589; Chromosome 16.
DR Bgee; ENSMUSG00000022668; Expressed in right kidney and 213 other cell types or tissues.
DR ExpressionAtlas; F6XXP5; baseline and differential.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01876; YihA_EngB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030393; G_ENGB_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR PANTHER; PTHR46498; GTP-BINDING PROTEIN 8; 1.
DR PANTHER; PTHR46498:SF1; GTP-BINDING PROTEIN 8; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51706; G_ENGB; 1.
PE 1: Evidence at protein level;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Proteomics identification {ECO:0007829|EPD:F6XXP5,
KW ECO:0007829|MaxQB:F6XXP5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 49..232
FT /note="EngB-type G"
FT /evidence="ECO:0000259|PROSITE:PS51706"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000123974.2"
SQ SEQUENCE 234 AA; 26340 MW; 310FF53AEC9CB2BA CRC64;
ALGPWTRVYS TSPAFAEVLR LPQKQLTKVV YPLRELGQHL AADSGPGLIE QRLFDPSLED
IGRAESIFEA TARNRIEYLS SAVRLDHAPS LQQPEGHTKK MNFFKVGKHF TLVDMPGYGY
RAPEDFVDMV ETYLKERNNL KRTFLLVDSV VGITKLDNIA IEMCEEFALP YVMILTKIDK
SSKGYLLKQV LQIQKFVNTQ TQGCFPQLFP ISAVTNSGVH LLKCFIADIT GSLK
//
