ID F6YEQ2_CIOIN Unreviewed; 615 AA.
AC F6YEQ2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCINP00000005107.3};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000005107.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000005107.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; EAAA01001165; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F6YEQ2; -.
DR Ensembl; ENSCINT00000005107.3; ENSCINP00000005107.3; ENSCING00000002503.3.
DR GeneTree; ENSGT00940000165024; -.
DR HOGENOM; CLU_008905_3_0_1; -.
DR Proteomes; UP000008144; Chromosome 14.
DR CDD; cd00033; CCP; 5.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 5.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR19325:SF567; LOCOMOTION-RELATED PROTEIN HIKARU GENKI; 1.
DR Pfam; PF00084; Sushi; 5.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00032; CCP; 5.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 5.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50923; SUSHI; 5.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 33..101
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 102..167
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 215..277
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 289..352
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 353..415
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 424..604
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 615 AA; 66068 MW; 46A70FA440FA8C0C CRC64;
MTGSTASRCV LTSQTSAAFD RAPPTCTPLQ DLPQCEPQQR APDHGSVQCT NTNLIGSVCT
FSCGSGYYLS GSINVLICGK LRNSVCIYSV TWSSPAPTCE PITCIPSHTS PTNGQVTCSN
GNLVGSECVF TCSPGYAVTG EPVSICNQVN IGTPAGVWSS PPPTCQLYFF TTAITCIPQQ
IPPTNGAVTC DNSNNLVTIR SNYTDCSNMR CYTELKCNPP QSNPTNGSVS CSDENNVNSE
CEFACMLGFT MVGEPITDCL MSGGVPAWTN VAPVCGRNIK NVWGYVKGSR CSNPPSAPTN
GYRVCSDGNY VGSICDYGCD DLYTRVGSQY STCVELADGS HSFDNPAPTC ERSSCRDVQT
LPNGNVSCSD GNFINSVCTY DCNAGNAYAL FPTNHSTTTC LNDTTWDLPP PCCARRCPPY
ALMDFVMILD SSSSVRRRNW RIMKNFGRSI IETFRLAEDA ARMAAFRYNR VVDTRSQILF
RQHVNDMAGF LASYNAIPYN GGGTLTGQAL RHAKDVILAR RNGNRPNVKD VVLTITDGRS
HDNVANVSRE LREMGVLTFV VGVVPGNGKQ LDENQLLSIA GSRSNMFLAT SGFSGLNSAF
SARLSESICT NPCAH
//
