ID   F6YKH2_XENTR            Unreviewed;       961 AA.
AC   F6YKH2; A0A5S6P5N6;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 4.
DT   27-MAR-2024, entry version 65.
DE   SubName: Full=Leucine rich repeat and coiled-coil centrosomal protein 1 {ECO:0000313|Ensembl:ENSXETP00000030189};
GN   Name=lrrcc1 {ECO:0000313|Ensembl:ENSXETP00000030189};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000030189};
RN   [1] {ECO:0000313|Ensembl:ENSXETP00000030189}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000030189};
RX   PubMed=20431018; DOI=10.1126/science.1183670;
RA   Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA   Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA   Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA   Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA   Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA   Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA   Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA   Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA   Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT   "The genome of the Western clawed frog Xenopus tropicalis.";
RL   Science 328:633-636(2010).
RN   [2] {ECO:0000313|Ensembl:ENSXETP00000030189}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
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DR   AlphaFoldDB; F6YKH2; -.
DR   Ensembl; ENSXETT00000030189; ENSXETP00000030189; ENSXETG00000013785.
DR   AGR; Xenbase:XB-GENE-992687; -.
DR   Xenbase; XB-GENE-992687; lrrcc1.
DR   eggNOG; KOG0531; Eukaryota.
DR   HOGENOM; CLU_011297_1_0_1; -.
DR   TreeFam; TF329470; -.
DR   Bgee; ENSXETG00000013785; Expressed in testis and 11 other cell types or tissues.
DR   ExpressionAtlas; F6YKH2; differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45973:SF13; LEUCINE RICH REPEAT AND COILED-COIL CENTROSOMAL PROTEIN 1; 1.
DR   PANTHER; PTHR45973; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED; 1.
DR   Pfam; PF12799; LRR_4; 1.
DR   SMART; SM00365; LRR_SD22; 5.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS51450; LRR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   REGION          232..337
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          373..509
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          537..571
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          618..687
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          713..870
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          901..935
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        233..259
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..323
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   961 AA;  110364 MW;  D43354CFA9691EE4 CRC64;
     MASTAPGSRE LSLMDKQIRN LLEICLHSHL YSINLHCNHI SKIEGLGHLC YLQHLDLSSN
     LITKIEGLDS LTCLQSLNLS CNKLTWVEGL GKLFNLKKLN LSYNRIQDLT GFIPLHGRNH
     KLSHLYLHSN CINNIEEVLQ SMVGLNCLLH LTLEQNAKGN PVCNVLGYRE IILENLPQLN
     SLDGIDRSGV PVTAHEVDSM DLANLDFLEY LINFDSGRKE VKASCPISEQ TTLKAKRDTD
     FTTESDSESS KDNRKGSTTR TPGCRKTSQA SKHQKHQASQ QSKGRTSVGE PKQNVSRKQP
     LSKTQSKADI ETSVSSGRTG STGQIPGKPH ALEGSLKKKG ELIRNATEES TYRALVQDLD
     QERERRWKAE QVVLKLTDSI KELQNQAKEE KDVNSMAVYT TDRIKELLFK EKSAKSKLQE
     LIHHLKEENQ KLADELKKLK DKEEDYQRAY KSMDDTLAKL ETQRIQQAAL EMKQVQEAER
     KVSASQREID LLRASLRQQK EKVHQLHELL TSKEQLHRKE LEARVALNGP EFQDALAKEM
     AKEAHRHSQE IHSFQEKMNL LTRQYADLED EFRAALIIEA GRFKDVKDGF DNVAAELAEH
     KEIVNRCLQK EKQSATLIQE LTAMVKEQKA RIAEITKAKQ DIISDLKSKI HSLEKVAEEG
     RQKTVQIELL KQEKSKLISQ LTAQESLIDG LKAERKIWGQ ELTQQGVSLA QDRGRLEAKI
     EVLSTEIESL KKQNERDTDT LRIKTKVVDD QTETIRKLKE GLQERDERIR KLREENIQLE
     KTLREQSDER TTQLEELKEK LERQTERKEE VKQLLEEKES ELEDVKKAYS AMNKKWQDKA
     ELLSQLETQV RQMKENFDAK ERKLIEERDK SLQSQKVTTE KLRSVDDAFR RQLESVLSAH
     QAELIKLASD KQKEIEAANE RVYQVEEEMR QLLKETANSK KIMEAKIKRL TGAFSDIQKE
     F
//