ID F6Z3E3_CIOIN Unreviewed; 374 AA.
AC F6Z3E3;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=UDP-galactopyranose mutase-like {ECO:0000313|Ensembl:ENSCINP00000015018.3};
GN Name=LOC100179743 {ECO:0000313|Ensembl:ENSCINP00000015018.3};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000015018.3, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000015018.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase
CC family. {ECO:0000256|ARBA:ARBA00009321}.
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DR EMBL; EAAA01001310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F6Z3E3; -.
DR STRING; 7719.ENSCINP00000015018; -.
DR Ensembl; ENSCINT00000015018.3; ENSCINP00000015018.3; ENSCING00000007316.3.
DR GeneTree; ENSGT00390000001788; -.
DR HOGENOM; CLU_042118_0_0_1; -.
DR InParanoid; F6Z3E3; -.
DR OMA; INVHKYG; -.
DR TreeFam; TF330079; -.
DR Proteomes; UP000008144; Chromosome 14.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IBA:GO_Central.
DR GO; GO:0008767; F:UDP-galactopyranose mutase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 3.
DR InterPro; IPR004379; UDP-GALP_mutase.
DR InterPro; IPR015899; UDP-GalPyranose_mutase_C.
DR NCBIfam; TIGR00031; UDP-GALP_mutase; 1.
DR PANTHER; PTHR21197; UDP-GALACTOPYRANOSE MUTASE; 1.
DR PANTHER; PTHR21197:SF0; UDP-GALACTOPYRANOSE MUTASE; 1.
DR Pfam; PF03275; GLF; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144}.
FT DOMAIN 145..350
FT /note="UDP-galactopyranose mutase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03275"
SQ SEQUENCE 374 AA; 44087 MW; 9FBB1A3879241FB6 CRC64;
HLIVGCGLSG SVIAERIANV WNENALIIEK REHIGGNCYD YVDDQTGIRM NKYGAHLFHT
KDEGVWKYVQ TFDKWTRWEH RVLSMVDGQF VPVPVNITTV NQVCGENIED TEEMDAWLSA
VQYKGPIENS EDMAVSRVGR VLYEKMFKPY TVKQWNKGPE ELDPSVLARI PIRRDFDVRY
FSDKYQALPA KGYTHFFERL LDNPRIQVQT GVDFFKYKLE HDLGQFKSIF YTGPIDQYFD
GLKLESLEYR SIDFHIERFS DMNYFQPCSV VNYPETNVPF TRIVEYKHFL NQTSKHTVTV
KETTNDHGDP YYPIPNKRNM ELYECYRQMA VKEEKEKNVH FVGRLANYKY MNMDQAIRNA
LDLFDRINSK EEMN
//
