ID F7A102_CIOIN Unreviewed; 452 AA.
AC F7A102;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Cilium assembly protein DZIP1 N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000029077.2, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000029077.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC {ECO:0000256|ARBA:ARBA00004536}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome, centriolar satellite
CC {ECO:0000256|ARBA:ARBA00004607}.
CC -!- SIMILARITY: Belongs to the ADIP family.
CC {ECO:0000256|ARBA:ARBA00009291}.
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DR EMBL; EAAA01002198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F7A102; -.
DR STRING; 7719.ENSCINP00000029077; -.
DR Ensembl; ENSCINT00000029323.2; ENSCINP00000029077.2; ENSCING00000016996.2.
DR GeneTree; ENSGT00390000007688; -.
DR HOGENOM; CLU_606287_0_0_1; -.
DR InParanoid; F7A102; -.
DR OMA; QHCKEMI; -.
DR TreeFam; TF332889; -.
DR Proteomes; UP000008144; Chromosome 5.
DR GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR GO; GO:0034451; C:centriolar satellite; IBA:GO_Central.
DR GO; GO:0036064; C:ciliary basal body; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0035735; P:intraciliary transport involved in cilium assembly; IBA:GO_Central.
DR InterPro; IPR021622; Afadin/alpha-actinin-bd.
DR PANTHER; PTHR46507; AFADIN- AND ALPHA-ACTININ-BINDING PROTEIN; 1.
DR PANTHER; PTHR46507:SF4; SSX FAMILY MEMBER 2 INTERACTING PROTEIN; 1.
DR Pfam; PF11559; ADIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144}.
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 270..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 452 AA; 53009 MW; 8254FE9E3FC3412C CRC64;
MESSEAGSVS SRSRSSSNQS SSDMFSKKHL TFCSPDTLLQ RAEFLNQEIS VLGYPAILVD
DALDPVAMIN VLHDLVNSYR QLLSCNSEIS TELKSSECES ARLEHLLLQA KDDVANIDRS
LKSKCSEVSY VNEKFESFRK KLRIEQEKCR RLSLDLINRD AQYKHEKKKK AQEVERMQTK
LQQLLQDKRH EKVLGIDMLN LMERPEGRRG KWTTEKSKKN NELEMYHMII NNYEDANKKL
LEENSEIRKY LKQMQEELIT ALNEKSAANI ADGNQGTNES GSKPDLVNGG VKISEPIRDN
LFEMPYEMVK DDIERNLTLR WKAVQKEIQN KNLQTTVPDM NYIIVIQRIN EHLYEMMRKM
EECKKIIEEQ QRLIDYLTTS QASTSSQHFS DSYFLEEKSE LERNKGMFYQ QRISFEKERQ
VYTDALIQLG IDRQKFEEQR SRWLQKHFLQ LT
//
