ID F7A7U9_CIOIN Unreviewed; 547 AA.
AC F7A7U9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 18-APR-2012, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=LRRCT domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia;
OC Cionidae; Ciona.
OX NCBI_TaxID=7719 {ECO:0000313|Ensembl:ENSCINP00000025751.2, ECO:0000313|Proteomes:UP000008144};
RN [1] {ECO:0000313|Proteomes:UP000008144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12481130; DOI=10.1126/science.1080049;
RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., De Tomaso A.,
RA Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., Harafuji N.,
RA Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., Lemaire P.,
RA Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., Putnam N., Rash S.,
RA Saiga H., Satake M., Terry A., Yamada L., Wang H.G., Awazu S., Azumi K.,
RA Boore J., Branno M., Chin-Bow S., DeSantis R., Doyle S., Francino P.,
RA Keys D.N., Haga S., Hayashi H., Hino K., Imai K.S., Inaba K., Kano S.,
RA Kobayashi K., Kobayashi M., Lee B.I., Makabe K.W., Manohar C., Matassi G.,
RA Medina M., Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A.,
RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M.,
RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., Stainier D.,
RA Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., Yoshizaki F.,
RA Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., Doggett N.,
RA Glavina T., Hawkins T., Richardson P., Lucas S., Kohara Y., Levine M.,
RA Satoh N., Rokhsar D.S.;
RT "The draft genome of Ciona intestinalis: insights into chordate and
RT vertebrate origins.";
RL Science 298:2157-2167(2002).
RN [2] {ECO:0000313|Ensembl:ENSCINP00000025751.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; EAAA01002875; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; F7A7U9; -.
DR STRING; 7719.ENSCINP00000025751; -.
DR Ensembl; ENSCINT00000025997.2; ENSCINP00000025751.2; ENSCING00000014175.2.
DR GeneTree; ENSGT00940000161095; -.
DR HOGENOM; CLU_498365_0_0_1; -.
DR InParanoid; F7A7U9; -.
DR OMA; NCESPED; -.
DR TreeFam; TF342742; -.
DR Proteomes; UP000008144; Chromosome 9.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24369; ANTIGEN BSP, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR24369:SF210; CHAOPTIN-RELATED; 1.
DR Pfam; PF13855; LRR_8; 2.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00365; LRR_SD22; 3.
DR SMART; SM00369; LRR_TYP; 6.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008144};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..547
FT /note="LRRCT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003348319"
FT TRANSMEM 437..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 364..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 547 AA; 61867 MW; 81AD31C347FE877C CRC64;
MTFSSAQVFL CLGLQLLFHE TISASPTKHC SNKGNVQRCH YQYLSRILRC DGRSRNSLPS
PTELQGPAPP STALSIYINS SCLQEIDSGQ LRQYTHAKQL NYDDNMIQTI PKSCFSHLHL
EELILSRNSI STINSAFNGL SHLKTLHLNG NQLQEILDDH FSELLSLTSL DLSDNMLTYV
HRNAFEGLTS LTSLDLSNNR LTKFEPGHLS GLVNLNKLRL RSNHLQSLDS HLLVSSPHLE
VVDLSFNRLQ CLPANLFDNQ SDLKSVLLMS NQLRTPHPDW FRSIVANGRM PDVNLMQNNK
WLCDCHSISY RNFLLNEITE HEDQWIDKLD VRCFQPATNE GKYLSDVKHF GSNCPYPLEP
LECEQQESST RTTTTNVPRP TTTTTTTKST TTEKSTTIKA KINSRSQVTT TITLPVNTPL
VLNLGADLPT KEDKSPLMII IISLVAVLCF AILGMAVYCM RRKWKKEKLV KKQNNNRMTN
KDDEAGQNLY EEPEIKMDDQ TIDNQTGPKL LYSASSLSLN EIEPQLYQAG EIPNPTNRKY
RKRTDSG
//
