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Database: UniProt
Entry: F7AA11_CALJA
LinkDB: F7AA11_CALJA
Original site: F7AA11_CALJA 
ID   F7AA11_CALJA            Unreviewed;      2375 AA.
AC   F7AA11;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   25-OCT-2017, entry version 30.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor type 3 {ECO:0000313|Ensembl:ENSCJAP00000022306};
GN   Name=ITPR3 {ECO:0000313|Ensembl:ENSCJAP00000022306};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000022306, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000022306, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000022306}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCJAP00000022306}.
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DR   EMBL; ACFV01169259; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01169260; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01169261; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01169262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01169263; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01169264; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9483.ENSCJAP00000022306; -.
DR   Ensembl; ENSCJAT00000023583; ENSCJAP00000022306; ENSCJAG00000012111.
DR   eggNOG; KOG3533; Eukaryota.
DR   eggNOG; ENOG410XR97; LUCA.
DR   GeneTree; ENSGT00760000119152; -.
DR   InParanoid; F7AA11; -.
DR   OMA; VVVFYND; -.
DR   TreeFam; TF312815; -.
DR   Proteomes; UP000008225; Chromosome 4.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:Ensembl.
DR   GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0043235; C:receptor complex; IEA:Ensembl.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:Ensembl.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:Ensembl.
DR   GO; GO:0060291; P:long-term synaptic potentiation; IEA:Ensembl.
DR   GO; GO:0007613; P:memory; IEA:Ensembl.
DR   GO; GO:0051592; P:response to calcium ion; IEA:Ensembl.
DR   GO; GO:0050913; P:sensory perception of bitter taste; IEA:Ensembl.
DR   GO; GO:0050916; P:sensory perception of sweet taste; IEA:Ensembl.
DR   GO; GO:0050917; P:sensory perception of umami taste; IEA:Ensembl.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   SMART; SM00472; MIR; 1.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50919; MIR; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1913   1938       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1950   1968       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1980   2000       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2036   2061       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2081   2103       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2210   2233       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1     78       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       84    142       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     2341   2368       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2375 AA;  268751 MW;  65C6A96295170251 CRC64;
     XGAGHWNGLY RFKHLATGNY LAAEENPSYK GDASDPKAAG MGAQGRAGRR NAGEKIKYRL
     VAVPHGNDIA SLFELDPTTL QKTDSLVPRN SYVRLRHLCT NTWIQSTNVP IDVEEERPIR
     LMVGLGTCPT KEDKEAFAIV SVPVSEIRDL DFANDASSML ASAVEKLSEG FISQNDRRFV
     IQLLEDLVFF VSDVPNNGQN VLDIMVTKPN RERQKLMREQ NILKQVRVHS GGDEAGPGGQ
     ERDALNCRLS TPFQNNLSLL HITPTFKQFL TRKACVYLAQ KKSCGDFYRI YFDIRGASTL
     IRTRLQRNPA CFQGHVCQEE VEGLASPARL SRSHPFHHLP THLSSLSHVA LTLPAQGWPF
     SPRCPPLSPN LSLISQQRGG ASQVLVITDR FSVHLLWVTP HEAQCPMPAA PWLPSAMSSS
     SSLSCRYQLK LFARMCLDRQ YLAIDEISQQ LGVDLIFLCM ADEMLPFDLR ASFCHLMLHV
     HVDRDPQELV TPVKFARLWT EIPTAITIKD YDSNLNASRD DKKNKFASTM EFVEDYLNNV
     VSEAVPFANE EKNKLTFEVV SLAHNLIYFG FYSFSELLRL TRTLLGIIDC VQGPPAMLQA
     YEDPGGKNVR RSIQGVGHMM STMVLSRKQS VFGAPSLPTG ASAAEPLDRS KFEENEDIVV
     METKLKILEI LQFILNVRLD YRISYLLSVF KKEFVEVFPM QDSGADGTAP AFDSTTANMN
     LDRIGEQAEA MFGVGKTSSM LEVDDEGGRM FLRVLIHLTM HDYAPLVSGA LQLLFKHFSQ
     RQEAMHTFKQ VQLLISAQDV ENYKVIKSEL DRLRTMVEKS ELWVDKKGSG KGEEVEAGAA
     KDKKERPTDE EGFLHPPGEK SSENYQIVKG ILERLNKMCG VGEQMRKKQQ RLLKNMDAHK
     VMLDLLQIPY DKGDAKMMEI LRYTHQFLQK FCAGNPGNQA LLHKHLHLFL TPGLLEAETM
     QHIFLNNYQL CSEISEPVLQ HFVHLLATHG RHVQYLDFLH TVIKAEGKYV KKCQDMIMTE
     LTNAGDDVVV FYNDKASLTH LLDMMKAARD GVEDHSPLMY HISLVDLLAA CAEGKNVYTE
     IKCTSLLPLE DVVSVVTHED CITEVKMAYV NFVNHCYVDT REMKEIYTSN HIWTLFENFT
     LDMSSGLSPK REKRLPDPTL EKYVLSVVLD TINAFFSSPF SENSTSLQTH QTIVVQLLQS
     TTRLLECPWL QQQHRGSVEA CIRTLAMVAK GRAISLPMDL DAHISSMLSS GASCAAAVQR
     NTSSYKAAMR AFPRVTPTAN QWDYKNIIEK LQDIITALEE RLKPLVQAEL SVLVDVLHWP
     ELLFLEGSEA YQRCESGGFL SKLIQHTKDL MESEEKLCIK VLRTLQQMLL KKTKYGDRGN
     QLRKMLLQNY LQNRKSSSRG DLPDPIGTGQ YRLPLPLGPP FYCLDQDWSA IAATQCRLDK
     EGATKLVCDL ITSTKNEKIF QESIGLAIRL LDGGNTEIQK SFHNLMMSDK KSERFFKVLH
     DRMKRAQQET KSTVAVNMND LGSQPHEDRE PANPTTKGQG SRAGAWRDGA PRIRCAGRGH
     REWVAPATPG LAYRPHGLFL DASFLIPLLA GPQPAPGARV QSNEMGTSVL IMQPILRFLQ
     LLCENHNRDL QNFLRCQNNK TNYNLVCETL QFLDIMCGST TGGLGLLGLY INEDNVGLVI
     QTLETLTEYC QGPCHENQTC IVTHESNGID IITALILNDI SPLCKYRMDL VLQLKDNASK
     LLLALMESRH DSENAERILI SLRPQELVDV IKKAYLQEEE RENSEVSPRE VGHNIYILAL
     QLSRHNKQLQ HLLKPVPAQE EEEDPLAYYE NHTSQIEIVR QDRSMEQIVF PVPGICQFLT
     EETKHRLFTT TEQDEQGSKV SDFFDQSSFL HNEMEWQRKL RSMPLIYWFS RRMTLWGSIS
     FNLAVFINII IAFFYPYVEG ASTGVLDSPL ISLLFWILIC FSIAALFTKS YSIRPLIVAL
     ILRSIYYLGI GPTLNILGAL NLTNKIVFVV SFVGNRGTFI RGYKAMVMDV EFLYHVGYIL
     TSVLGLFAHE LFYSILLFDL IYREETLFNV IKSVTRNGRS ILLTALLALI LVYLFSIVGF
     LFLKDDFILE VDRLPNNHSR ASPLGMPHGA AAFVGTCSRD KMDCVSGVSV PEVLEEDGEL
     DSTERACDTL LMCIVTVMNH GLRNGGGVGD ILRKPSKDES LFPARVVYDL LFFFIVIIIV
     LNLIFGVIID TFADLRSEKQ KKEEILKTTC FICGLERDKF DNKTVSFEEH IKLEHNMWNY
     LYFIVLVRVK NKTDYTGPES YVAQMIKNKN LDWFPRMRAM SLVSNEGEGE QNEIRILQDK
     LNSTMKLVSH LTAQLNELKE QMTEQRKRRQ RLGFV
//
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