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Database: UniProt
Entry: F7AJM0_CALJA
LinkDB: F7AJM0_CALJA
Original site: F7AJM0_CALJA 
ID   F7AJM0_CALJA            Unreviewed;       881 AA.
AC   F7AJM0;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   27-JUL-2011, sequence version 1.
DT   30-AUG-2017, entry version 40.
DE   SubName: Full=Transient receptor potential cation channel subfamily C member 6 {ECO:0000313|Ensembl:ENSCJAP00000001062};
GN   Name=TRPC6 {ECO:0000313|Ensembl:ENSCJAP00000001062};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000001062, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000001062, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000001062}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00788929}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSCJAP00000001062}.
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DR   EMBL; ACFV01085007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ACFV01085008; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9483.ENSCJAP00000001062; -.
DR   Ensembl; ENSCJAT00000001129; ENSCJAP00000001062; ENSCJAG00000000595.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   GeneTree; ENSGT00760000119180; -.
DR   InParanoid; F7AJM0; -.
DR   OMA; NRGPAYM; -.
DR   OrthoDB; EOG091G01FB; -.
DR   TreeFam; TF313147; -.
DR   Proteomes; UP000008225; Chromosome 11.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0036057; C:slit diaphragm; IEA:Ensembl.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:Ensembl.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IEA:Ensembl.
DR   GO; GO:0051928; P:positive regulation of calcium ion transport; IEA:Ensembl.
DR   GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; IEA:Ensembl.
DR   GO; GO:0032414; P:positive regulation of ion transmembrane transporter activity; IEA:Ensembl.
DR   CDD; cd00204; ANK; 1.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR005462; TRPC6_channel.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   PANTHER; PTHR10117:SF69; PTHR10117:SF69; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
DR   PRINTS; PR01647; TRPCHANNEL6.
DR   SMART; SM00248; ANK; 3.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 2.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00844120}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Ion channel {ECO:0000256|SAAS:SAAS00816195};
KW   Ion transport {ECO:0000256|SAAS:SAAS00816776};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00816535}.
FT   TRANSMEM    374    394       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    406    426       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    457    475       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    495    514       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    601    623       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    670    691       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       72    122       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   REPEAT      185    217       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   DOMAIN      185    217       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   COILED      835    870       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   881 AA;  101050 MW;  FB15BDBC89953952 CRC64;
     MDSELGEDGC PHAPLPSYGY YPCFRGSDNR LAHRRQTVLR EKGRRLANRG PAYMFSDRST
     SLSIEEERFL DAAEYGNIPV VRKMLEECLS LNVNCVDYMG QNALQLAVAN EHLEITELLL
     KKENLSRVGD ALLLAISKGY VRIVEAILSH PAFAEGKRLA TSPSQSELQQ DDFYAYDEDG
     TRFSHDVTPI ILAAHCQEYE IVHTLLRKGA RIERPHDYFC KCNDCNQKQK HDSFSHSRSR
     INAYKGLASP AYLSLSSEDP VMTALELSNE LAVLANIEKE FKNDYKKLSV QCKDFVVGLL
     DLCRNTEEVE AILNGDVETL QSGDHGRPNL SRLKLAIKYE VKKFVAHPNC QQQLLSIWYE
     NLSGLRQQTM VVKFLVVLAV AIGLPFLALI YWFAPCSKMG KIMRGPFMKF VAHAASFTIF
     LGLLVMNAAD RFEGTKLLPN ETSTDNAKQL FRMKTSCFSW MEMLIISWVI GMIWAECKEI
     WTQGPKEYLF ELWNMLDFGM LAIFAASFIA RFMAFWHASK AQSIIDANDT LKDLTKVTLG
     DNVKYYNLAR IKWDPSDPQI ISEGLYAIAV VLSFSRIAYI LPANESFGPL QISLGRTVKD
     IFKFMVIFIM VFVAFMIGMF NLYSYYIGAK QNEAFTTVEE SFKTLFWAIF GLSEVKSVVI
     NYNHKFIENI GYVLYGVYNV TMVIVLLNML IAMINSSFQE IEDDADVEWK FARAKLWFSY
     FEEGRTLPVP FNLVPSPKSL FYLLLKLKKW ISELFQSHKK DFQEDAEMNK GNDKERMNKL
     GHNKQASVRN SEDFRLNSFN NPPRQYQKIM KRLIKRYVLQ AQVDKESDEV NEGELKEIKQ
     DISSLRYELL EEKSQNTQDL AELIRELGEK LSMEPNQEKT N
//
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