ID F7B1T5_CALJA Unreviewed; 423 AA.
AC F7B1T5;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
GN Name=KRT25 {ECO:0000313|Ensembl:ENSCJAP00000025184.4};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000025184.4, ECO:0000313|Proteomes:UP000008225};
RN [1] {ECO:0000313|Ensembl:ENSCJAP00000025184.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCJAP00000025184.4}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; F7B1T5; -.
DR STRING; 9483.ENSCJAP00000025184; -.
DR Ensembl; ENSCJAT00000026616.4; ENSCJAP00000025184.4; ENSCJAG00000013664.3.
DR eggNOG; ENOG502QTH0; Eukaryota.
DR GeneTree; ENSGT00940000162192; -.
DR HOGENOM; CLU_012560_8_1_1; -.
DR InParanoid; F7B1T5; -.
DR TreeFam; TF332742; -.
DR Proteomes; UP000008225; Chromosome 5.
DR Bgee; ENSCJAG00000013694; Expressed in kidney and 2 other cell types or tissues.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF44; KERATIN, TYPE I CYTOSKELETAL 23; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000008225}.
FT DOMAIN 72..382
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 76..110
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 168..202
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 326..357
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 423 AA; 48214 MW; 044B083E5720756F CRC64;
MNSRHSFSQT PSASFHGAGG GWGRPRSFPR APSVHGGAGG TQVSLSFTTR GCLPTTGSWD
SGRGSPLLGG NGKATMQNLN DRLTSYLEKV RALEEANMKL ESRILKWHQQ RDPVSKKDYS
QYEENITHLQ EQIVDGKMTN AQIILLIDNA RMAVDDFNLK YENEHSFKKD LEIEVEGLRR
TLDNLTIVTT DLEQEVEGMR KELILMKKHH EQEMEKQHVP SDLKVNVKVD TGPREDLIKV
LEDMRQEYEL IIKKKHQDLD TWYKEQSAAM SQEAASPAAM QSRQGDIHEL KRTFQALEID
LQAQYSTKSA LENMLSETQS RYSCKLQDMQ DIISHYEEEL MQLRHDLERQ NNEYQVLLGI
KTHLEKEITT YRQLLEGESE GMVVTSSVLF FSASATSKIK AITQETINGR LVLCQVNEIQ
KQA
//
