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Database: UniProt
Entry: F7B9H3_MACMU
LinkDB: F7B9H3_MACMU
Original site: F7B9H3_MACMU 
ID   F7B9H3_MACMU            Unreviewed;      1092 AA.
AC   F7B9H3;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   30-NOV-2016, sequence version 2.
DT   30-AUG-2017, entry version 49.
DE   SubName: Full=Potassium voltage-gated channel subfamily H member 7 {ECO:0000313|Ensembl:ENSMMUP00000025734};
GN   Name=KCNH7 {ECO:0000313|Ensembl:ENSMMUP00000025734};
OS   Macaca mulatta (Rhesus macaque).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9544 {ECO:0000313|Ensembl:ENSMMUP00000025734, ECO:0000313|Proteomes:UP000006718};
RN   [1] {ECO:0000313|Ensembl:ENSMMUP00000025734, ECO:0000313|Proteomes:UP000006718}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000025734,
RC   ECO:0000313|Proteomes:UP000006718};
RX   PubMed=17431167; DOI=10.1126/science.1139247;
RA   Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M.,
RA   Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C.,
RA   Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W.,
RA   Hardison R.C., Makova K.D., Miller W., Milosavljevic A., Palermo R.E.,
RA   Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J.,
RA   Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y.,
RA   Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T.,
RA   Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J.,
RA   Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A.,
RA   Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M.,
RA   Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D.,
RA   Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J.,
RA   Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E.,
RA   Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S.,
RA   Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X.,
RA   Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E.,
RA   Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M.,
RA   Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M.,
RA   Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y.,
RA   Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E.,
RA   Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J.,
RA   Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J.,
RA   Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A.,
RA   Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J.,
RA   Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A.,
RA   Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B.,
RA   Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S.,
RA   Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V.,
RA   Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A.,
RA   Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C.,
RA   Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P.,
RA   Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E.,
RA   Zwieg A.S.;
RT   "Evolutionary and biomedical insights from the rhesus macaque
RT   genome.";
RL   Science 316:222-234(2007).
RN   [2] {ECO:0000313|Ensembl:ENSMMUP00000025734}
RP   IDENTIFICATION.
RC   STRAIN=17573 {ECO:0000313|Ensembl:ENSMMUP00000025734};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSMMUP00000025734}.
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DR   EMBL; JSUE03008995; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03008996; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; JSUE03008997; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9544.ENSMMUP00000025734; -.
DR   Ensembl; ENSMMUT00000027515; ENSMMUP00000025734; ENSMMUG00000019591.
DR   eggNOG; KOG0498; Eukaryota.
DR   eggNOG; ENOG410XPSE; LUCA.
DR   GeneTree; ENSGT00760000118772; -.
DR   InParanoid; F7B9H3; -.
DR   OrthoDB; EOG091G024C; -.
DR   TreeFam; TF313130; -.
DR   Proteomes; UP000006718; Chromosome 12.
DR   Bgee; ENSMMUG00000019591; -.
DR   ExpressionAtlas; F7B9H3; baseline.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:GO_Central.
DR   GO; GO:0042391; P:regulation of membrane potential; IBA:GO_Central.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR018490; cNMP-bd-like.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
DR   InterPro; IPR003967; K_chnl_volt-dep_ERG.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01463; EAGCHANLFMLY.
DR   PRINTS; PR01470; ERGCHANNEL.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; SSF51206; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006718};
KW   Ion channel {ECO:0000256|SAAS:SAAS00091826};
KW   Ion transport {ECO:0000256|SAAS:SAAS00502700};
KW   Membrane {ECO:0000256|SAAS:SAAS00502630, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00807593};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00807732};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00807568};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006718};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00137614,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00137754,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00502637};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00807693}.
FT   TRANSMEM    308    329       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    445    469       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    510    529       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    541    562       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      641    741       Cyclic nucleotide-binding.
FT                                {ECO:0000259|PROSITE:PS50042}.
FT   COILED      924    951       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1092 AA;  123201 MW;  398F3A212744F44D CRC64;
     STFICNTHII PVKNQEGVAM MFIINFEYVT DENAATPERV NPILPVKTVN RKFFGFKFPG
     LRVLTYRKQS LPQEDPDVVV IDSSKHSDDS VAMKHFKSPT KESCSPSEAD DTKALIQPSK
     CSPLVNISGP LDHSSPKRQW DRLYPDMLQS SSQLSHSRSR ESLCSIRRAS SVHDIEGFSV
     HPKNIFRDRH ASEDNGRNVK GPFNHIKSSL LGSTSDSNLN KYSTINKIPQ LTLNFSEAKT
     EKKNSSPPSS DKTIIAPKVK DRTHNVTEKV TQVLSLGADV LPEYKLQTPR INKFTILHYS
     PFKAVWDWLI LLLVIYTAIF TPYSAAFLLN DREEQKRREC GYSCSPLNVV DLIVDIMFII
     DILINFRTTY VNQNEEVVSD PAKIAIHYFK GWFLIDMVAA IPFDLLIFGS GSDETTTLIG
     LLKTARLLRL VRVARKLDRY SEYGAAVLML LMCIFALIAH WLACIWYAIG NVERPYLTDK
     IGWLDSLGQQ IGKRYNDSDS SSGPSIKDKY VTALYFTFSS LTSVGFGNVS PNTNSEKIFS
     ICVMLIGSLM YASIFGNVSA IIQRLYSGTA RYHMQMLRVK EFIRFHQIPN PLRQRLEEYF
     QHAWTYTNGI DMNMVLKGFP ECLQADICLH LNQTLLQNCK AFRGASKGCL RALAMKFKTT
     HAPPGDTLVH CGDVLTALYF LSRGSIEILK DDIVVAILGK NDIFGEMVHL YAKPGKSNAD
     VRALTYCDLH KIQREDLLEV LDMYPEFSDH FLTNLELTFN LRHESAKADL LRSQSMNDSE
     GDNCKLRRRK LSFESEGEKE NSTNDPEDSA DTIRHYQSSR RHFEEKKSRS SSFISSIDDE
     QKPLFSGIVD SSPGIGKASG LDFEETVPTS GRMHIDKRSH SCKDITDMRS WERENAHPQP
     EDSSPSALQR AAWGISETES DLTYGEVEQR LDLLQEQLNR LESQMTTDIQ TILQLLQKQT
     TVVPPAYSMV TAGAEYQRPI IRLMRTSQPA ASIKTDRSFS PSSQCPEFLD LEKSKLKSKE
     SLSSGVHLNT ASEDNLTSLL KQDSDLSLEL HLRQRKTYLH PIRHPSLPDS SLSTVGILGL
     HRHVSDPGLP GK
//
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