ID F7BJN0_XENTR Unreviewed; 727 AA.
AC F7BJN0;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 4.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Muskelin {ECO:0000313|Ensembl:ENSXETP00000039414, ECO:0000313|RefSeq:XP_002931895.1};
GN Name=mkln1 {ECO:0000313|Ensembl:ENSXETP00000039414,
GN ECO:0000313|RefSeq:XP_002931895.1,
GN ECO:0000313|Xenbase:XB-GENE-976014};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000039414};
RN [1] {ECO:0000313|Ensembl:ENSXETP00000039414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000039414};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [2] {ECO:0000313|Ensembl:ENSXETP00000039414}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [3] {ECO:0000313|RefSeq:XP_002931895.1}
RP IDENTIFICATION.
RC STRAIN=Nigerian {ECO:0000313|RefSeq:XP_002931895.1};
RC TISSUE=Liver and blood {ECO:0000313|RefSeq:XP_002931895.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_002931895.1; XM_002931849.5.
DR Ensembl; ENSXETT00000039414; ENSXETP00000039414; ENSXETG00000018173.
DR GeneID; 100489031; -.
DR KEGG; xtr:100489031; -.
DR AGR; Xenbase:XB-GENE-976014; -.
DR CTD; 4289; -.
DR Xenbase; XB-GENE-976014; mkln1.
DR eggNOG; KOG2437; Eukaryota.
DR HOGENOM; CLU_004210_1_0_1; -.
DR OMA; NKQDYKH; -.
DR TreeFam; TF323659; -.
DR Proteomes; UP000008143; Chromosome 3.
DR Bgee; ENSXETG00000018173; Expressed in liver and 12 other cell types or tissues.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR010565; Muskelin_N.
DR PANTHER; PTHR15526; MUSKELIN; 1.
DR PANTHER; PTHR15526:SF5; MUSKELIN; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR Pfam; PF13415; Kelch_3; 1.
DR Pfam; PF06588; Muskelin_N; 1.
DR SMART; SM00667; LisH; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR PROSITE; PS50022; FA58C_3; 1.
DR PROSITE; PS50896; LISH; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 1..147
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
SQ SEQUENCE 727 AA; 84333 MW; C7F4E7C5BBA5153A CRC64;
MAAEIRGLPY AVFKWSSFSS SYLPENILVD KPNDQSSRWS SENNNPPQYL ILKLERPAIL
QSITFGKYEK THVCNLKKFK VFGGMNEENM TELLSSGLKN DYNKETFTLK HKIDEQMFPC
RFIKIVPLLS WGPSFNFSIW YVEINGIDEP DVVQPCLHWY SKYREQEAIR LCLKHFRQHN
YTEAFESLQK KTKIALEHPM LTELHDKLVL KGDFDSCEAL IEKAVNDGLF SQYISQQEYK
PQWNQIIPKI TKGDGEDSRP GMRGGHQMVI DVQSEMVYLF GGWDGTQDLA DFWAYSVGEN
QWICISRDTE KENGPSARSC HKMCIDTQRR QIYTLGRYLD SSVRNSKSLK SDFYCYDIDT
NTWTLLSEDT SADGGPKLVF DHQMCMDSEK HMIYTFGGRI LTCNGSVDDS RANEPQFSGL
FAFDCHSQTW KLLREDSCNA GPEDIQSRIG HCMLFHSKNR CLYVFGGQRS KTYLNDFFSY
DVDRDHVEII SDGTKKDSGM VPMTGFTQRA TIDPELNEIH VLSGLSKDKE KREENVRNSF
WIYDIVRNSW SCVYKNDQAS KENTNKNAQE EEPCPRFAHQ LVYDELHKVH YLFGGNPGKS
CSPKMRLDDF WSLKLCRPSK EYLLRHCKYL IRKHRFEERA QTEPLSALKY LQNDLFVTVD
HSDPEETKEF QLLPSALFKS NKDFTPLGFS DVDHTYFQRT QLFDVLVNFF PDSMTPPKGN
LVDLITL
//
