ID F7CGH2_HORSE Unreviewed; 602 AA.
AC F7CGH2;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 3.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Leucine rich repeat containing 40 {ECO:0000313|Ensembl:ENSECAP00000017271.3};
GN Name=LRRC40 {ECO:0000313|Ensembl:ENSECAP00000017271.3,
GN ECO:0000313|VGNC:VGNC:58668};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000017271.3, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000017271.3, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000017271.3,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000017271.3}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000017271.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; F7CGH2; -.
DR Ensembl; ENSECAT00000020999.4; ENSECAP00000017271.3; ENSECAG00000019554.4.
DR VGNC; VGNC:58668; LRRC40.
DR GeneTree; ENSGT00940000156968; -.
DR TreeFam; TF354310; -.
DR Proteomes; UP000002281; Chromosome 5.
DR Bgee; ENSECAG00000019554; Expressed in brainstem and 23 other cell types or tissues.
DR ExpressionAtlas; F7CGH2; baseline.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF1; ZGC:77287; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 4.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00364; LRR_BAC; 11.
DR SMART; SM00365; LRR_SD22; 6.
DR SMART; SM00369; LRR_TYP; 13.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS51450; LRR; 11.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000002281};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ SEQUENCE 602 AA; 68264 MW; 51671645664CFE01 CRC64;
MSRLKGVADR DSRTGFRAER RDCGASVPQG LLKAARKSGQ LNLSGRNLSE VPQCVWRINV
DIPEEANQNL SFSAAERWWE QTDLTKLIIS NNKLQSLTDD LRLLPALTVL DIHDNQLTSL
PSAIRELENL QKLNVSHNKL KILPEEITNL RNLKGLYLQH NELTCLPEGF EQLFSLEDLD
LSNNRLTIVP ASFSSLSSLV RLNLSSNQLK SLPAEISGMK RLKHLDCNSN LLETIPPELA
SMESLELLYL RRNKLRFLPE FPSCKLLKEL HVGENQIEML GAEHLKHLNS ILVLDLRDNK
LKSVPDEITL LQSLERLDLS NNDISSLPYS LGKLHLKFLA LEGNPLRTIR REIINKGTQE
VLKYLQSKIK DDEPSQNNSV TETAMTLPSE SRVNVHSIVT LKILDYSDKQ AVLIPDEVFD
AVKSNIVTSV NFSKNQLCEI PKRIIELKEM VSDVNLSFNK LSFVSLELCT LQKLTFLDLR
NNFLNSLPEE MESLIRLQTI NLSFNRFKIL PEVLYRIPTL ETILISNNQV GSVDPQKMKT
MENLITLDLQ NNDLLQIPPE LGNCVNLRTL LLDGNPFRVP RAAILMKGTA AILEYLRDRI
PT
//
