ID F7CHW9_HORSE Unreviewed; 278 AA.
AC F7CHW9;
DT 27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT 13-SEP-2023, sequence version 4.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Regulator of G protein signaling 9 {ECO:0000313|Ensembl:ENSECAP00000015889.4};
GN Name=RGS9 {ECO:0000313|Ensembl:ENSECAP00000015889.4,
GN ECO:0000313|VGNC:VGNC:22357};
OS Equus caballus (Horse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000015889.4, ECO:0000313|Proteomes:UP000002281};
RN [1] {ECO:0000313|Ensembl:ENSECAP00000015889.4, ECO:0000313|Proteomes:UP000002281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000015889.4,
RC ECO:0000313|Proteomes:UP000002281};
RX PubMed=19892987; DOI=10.1126/science.1178158;
RG Broad Institute Genome Sequencing Platform;
RG Broad Institute Whole Genome Assembly Team;
RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
RA Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
RA Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
RA Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
RA Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
RA Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
RA Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
RA Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
RA Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
RT "Genome sequence, comparative analysis, and population genetics of the
RT domestic horse.";
RL Science 326:865-867(2009).
RN [2] {ECO:0000313|Ensembl:ENSECAP00000015889.4}
RP IDENTIFICATION.
RC STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000015889.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 9796.ENSECAP00000049545; -.
DR PaxDb; 9796-ENSECAP00000049545; -.
DR Ensembl; ENSECAT00000019414.4; ENSECAP00000015889.4; ENSECAG00000029829.3.
DR VGNC; VGNC:22357; RGS9.
DR GeneTree; ENSGT00940000156505; -.
DR HOGENOM; CLU_025092_5_0_1; -.
DR OMA; PRMACLR; -.
DR TreeFam; TF351956; -.
DR Proteomes; UP000002281; Chromosome 11.
DR Bgee; ENSECAG00000029829; Expressed in retina and 16 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0043005; C:neuron projection; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF1; REGULATOR OF G-PROTEIN SIGNALING 9; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR SMART; SM00049; DEP; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002281}.
FT DOMAIN 30..105
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
SQ SEQUENCE 278 AA; 32007 MW; D1F41B86364A5051 CRC64;
MTIRHQGQQY RPRMAFLQKI EALVKDMQNP ETGIKMQNQK VLVTSVPHAM TGSDVLQWIV
QRLWISNLEA QNLGNFVVKY GYIYPLQDPK NLILKPDGSL YRFQTPYFWP TQQWPAEDTD
YAIYLAKRNI KKKGILEEYE KENYYFLNKK INYKWDFVIM QAKEQYRAGK ERNKADRYAL
DCQEKAYWLV HRCPPGMNNV LDYGLDRVTN PNEVQVNQLS FSCLHSGCCG VLRRIKNCNS
HAGAPSPQPA PASVSDPAVR GTEAGAVLDL FATFTTVD
//
